李 晓,马恒敏,马学真.2014—2019年山东省青岛市城市居民结直肠癌早诊早治项目筛查结果分析[J].中国肿瘤,2021,30(5):340-345.
2014—2019年山东省青岛市城市居民结直肠癌早诊早治项目筛查结果分析
Screening Results of Early Diagnosis and Treatment of Colorectal Cancer Among Urban Residents in Qingdao City from 2014 to 2019
中文关键词  修订日期:2020-07-21
DOI:10.11735/j.issn.1004-0242.2021.05.A004
中文关键词:  结直肠癌  结肠镜  筛查  早诊早治  山东
英文关键词:colorectal cancer  colonoscopy  screening  early diagnosis and treatment  Shandong
基金项目:国家城市癌症早诊早治项目
作者单位
李 晓 青岛大学附属青岛市中心医院 
马恒敏 山东省肿瘤防治研究院(山东省肿瘤医院)山东第一医科大学(山东省医学科学院) 
马学真 青岛大学附属青岛市中心医院 
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中文摘要:
      摘 要:[目的] 分析总结2014—2019年青岛市城市居民结直肠癌高危人群的风险评估及临床筛查结果。[方法] 通过问卷初筛确定高危人群,通过结肠镜筛查进行精筛,对青岛市2个辖区的结直肠癌高危人群进行结直肠癌及癌前病变筛査,分析评估结直肠癌的高风险率、依从性和检出率。[结果] 2014—2019年共对103 229名居民进行危险因素调查,评估出结直肠癌高危人群10 582名,高风险率为10.25%。2735人完成结肠镜筛查,筛查依从性为25.85%(2735/10582)。高风险率和筛查依从性随年龄增加而增大。共有1557名完成病理活检,活检率为56.93%(1557/2735),共检出非瘤性息肉364例,检出率为13.31%(364/2735);非进展期腺瘤1071例,检出率为39.16%(1071/2735);进展期腺瘤114例,检出率为4.17%(114/2735),有随年龄增加而检出率升高的趋势;癌8例(包括早癌6例),检出率为0.29%(8/2735),另有癌前病变819例,早诊率为99.75%(825/827)。结直肠筛查依从性逐年提升。[结论] 城市癌症早诊早治项目是实现肿瘤“早发现、早诊断、早治疗”的有效途径,提高了项目高危人群结直肠癌早诊早治的比例。肿瘤健康宣教有利于提高肿瘤高危人群的“三早意识”(早发现、早诊断、早治疗),然而,结肠镜筛查的依从性受多方因素影响,除加强宣教外,可探索将肿瘤筛查纳入医保范围。
英文摘要:
      Abstract:[Purpose] To analyze the results of colorectal cancer screening among urban residents from 2014 to 2019 in Qingdao City. [Methods] According to the requirement of National Early Diagnosis and Treatment of Cancer Among Urban Residents Program,the colorectal cancer screening was conducted in two urban districts of Qingdao city. The questionnaire survey was conducted as the initial screening to identify high-risk population,and the identified high-risk subjects further underwent colonoscopy examination for clinical screening. The high-risk rate,compliance rate and detection rate of colorectal cancer were analyzed. [Results] A total of 103 229 residents participated in the risk assessment,and 10 582 individuals with high risk of colorectal cancer were identified with a high-risk rate of 10.25%. Among them 2735 subjects completed colonoscopy screening,with a compliance rate of 25.85%. The high-risk rates and screening compliance increased with age. A total of 1557 biopsies were performed with a biopsy rate of 56.93%(1557/2735). A total of 364 non-neoplastic polyps were detected,with a detection rate of 13.31%(364/2735). The detection rate of non-advanced adenomas was 39.16%(1071/2735). The detection rate of advanced adenomas was 4.17%(114/2735),which increased with age. Eight cases of colorectal cancer were detected with a cancer detection rate of 0.29%(8/2735),among whom 6 cases were early cancer;and 819 cases of precancerous lesions were detected with a total early diagnosis rate of 99.75%(825/827). The compliance rate was improved from 2014 to 2019. [Conclusion]The colorectal cancer screening program is effective to detect early cancer and precancerous lesions. However,the compliance of colonoscopy need to be further improved.
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