| 梁 岭,雷 林,蔡伟聪.2017—2019年广东省深圳市城市居民[J].中国肿瘤,2021,30(5):334-339. |
| 2017—2019年广东省深圳市城市居民 |
| Analysis of Liver Cancer Risk Assessment and Screening Results Among Urban Residents in Shenzhen，2017—2019 |
| 中文关键词 修订日期：2020-06-24 |
| DOI：10.11735/j.issn.1004-0242.2021.05.A003 |
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| 中文关键词: 肝癌 癌症筛查 早诊早治 城市 广东 |
| 英文关键词:liver cancer cancer screening early diagnosis and treatment urban Guangdong |
| 基金项目:深圳市医疗卫生三名工程（SZSM201911015）；广东省自然科学基金（2020A1515011478） |
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| 中文摘要: |
| 摘 要：［目的］分析2017—2019年广东省深圳市城市癌症早诊早治项目中肝癌高危评估与筛查情况。［方法］ 按照深圳市城市癌症早诊早治中肝癌筛查流程，选定社区年龄40~74岁的当地居民，问卷调查之后采用国家统一评估模型评估出高危人群，进一步通过肝脏B超+甲胎蛋白（alpha fetoprotein，AFP）检测，发现早期肝脏病变。［结果］ 2017—2019年度，深圳市城市癌症早诊早治项目共计36 457人完成危险因素问卷调查，评估出肝癌高危人群7038人，高风险率为19.30%（7038/36457）。男性肝癌高风险率（21.62%，3269/15117）显著高于女性（17.66%，3769/21340）（χ2=89.209，P<0.001）。3762人完成临床筛查，筛查率为53.45%（3762/7038）。经肝脏B超+AFP检测，共检出AFP阳性9例（检出率为0.24%，9/3762），肝硬化31例（检出率为0.82%，31/3762），肝占位33例（检出率为0.88%，33/3762），可疑肝癌2例（检出率为0.05%，2/3762）。［结论］通过问卷调查评估出高危人群后，采用肝脏B超结合AFP检测的筛查手段能够有效检出肝癌及癌前病变。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of liver cancer risk assessment and screening among urban residents in Shenzhen from 2017 to 2019. ［Methods］According to the liver cancer screening protocol in urban Shenzhen，the local residents aged 40~74 years from the selected communities were enrolled in the study. The high-risk populations were identified by evaluation with the national unified questionnaires. The high-risk individuals underwent liver ultrasonography and AFP tests for detection of early liver disease. ［Results］ During 2017—2019，a total of 36 457 residents completed questionnaire risk assessment，and 7038 subjects(19.30%) were identified to have high risk of liver cancer with a high-risk rate of liver cancer of 21.62%(3269/15117）in males and 17.66%(3769/21340) in females(χ2=89.209，P<0.001). A total of 3762 subjects participated in clinical screening with a compliance rate of 53.45%(3762/7038）. There were 9 cases of AFP positive(0.24%，9/3762)，31 cases of cirrhosis(0.82%，31/3762)，33 cases of occupying lesions in the liver(0.88%，33/3762)，and 2 cases of suspected liver cancer(0.05%，2/3762). ［Conclusion］ The protocol of liver cancer screening by questionnaire risk assessment combined with liver ultrasound and AFP detection is feasible and effective for detection of liver cancer and other liver lesions. |
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