| 郭兰伟,刘曙正,郑黎阳.2013—2019年河南省城市地区乳腺癌筛查结果分析[J].中国肿瘤,2021,30(4):292-299. |
| 2013—2019年河南省城市地区乳腺癌筛查结果分析 |
| Analysis of Breast Cancer Screening Results in Urban Areas of Henan Province，2013—2019 |
| 中文关键词 修订日期：2020-06-02 |
| DOI：10.11735/j.issn.1004-0242.2021.04.A008 |
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| 中文关键词: 乳腺癌 高危人群 筛查 河南 |
| 英文关键词:breast cancer high risk population screening Henan |
| 基金项目:河南省科技攻关计划（192102310353）；国家重大公共卫生服务专项—城市癌症早诊早治项目 |
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| 中文摘要: |
| 摘 要：［目的］ 评价2013—2019年河南省城市居民乳腺癌筛查依从性及筛查结果。［方法］ 采取整群抽样的方法，选取河南省40~74岁城市户籍居民进行癌症危险因素调查和乳腺癌风险评估。对于乳腺癌高危人群，40~44岁者行乳腺超声检查；45岁以上者行乳腺超声联合X线摄影（钼靶）检查。两种检查均以BI-RADS分类作为主要检查结果，以BI-RADS 3级为乳腺癌可疑阳性患者，BI-RADS 4级和5级为乳腺癌阳性患者。采用χ2检验分析不同组间人群的顺应性和乳腺癌检出率。［结果］ 本研究共纳入29 111名当地乳腺癌高危人群，年龄为（55.03±7.91）岁；共有13 760名接受了乳腺超声或钼靶检查，总体参与率为47.27%(13760/29111)。乳腺癌疑似阳性检出率为23.40%(3220/13760)，阳性检出率为2.55%(351/13760)，筛查人群随访后确诊乳腺癌检出率为0.30%(41/13760)。筛查人群中45~49岁年龄组乳腺癌可疑阳性率最高（27.79%），50~54岁年龄组阳性率为最高（2.98%），65~69岁年龄组乳腺癌检出率最高（0.49%）。乳腺超声联合钼靶检查阳性检出率为2.95%(316/10 728)，显著高于单独行乳腺超声（1.99%）或钼靶检查（1.25%）。［结论］ 乳腺癌高危人群行乳腺超声联合钼靶检查可显著提高乳腺癌阳性检出率。下一步应努力提高人群依从性以及筛查提供方的组织实施和服务能力，提高筛查效益。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of breast cancer screening in urban areas of Henan province from 2013 to 2019.［Methods］ A cluster sampling method was used to select the residents of 40～74 years old in Henan province to investigate the breast cancer risk. For subjects with high risk of breast cancer，those aged 40～44 conduct breast were subjected to ultrasound examination；those aged over 45 were subjected to breast ultrasound combined with mammography examination. BI-RADs classification was used as the evaluation standard in both examinations. BI-RADS 3 class was defined as suspected and BI-RADS≥4 class was defined as positive. Chi-square test was used to analyze the compliance rate and breast cancer detection rate among different groups. ［Results］ A total of 29 111 residents aged 55.03±7.91 years were identified as high risk for breast cancer，among whom 13 760 underwent breast ultrasound and/or mammography examination with a compliance rate of 47.27%. The detection rates of suspected positive patients，positive patients and breast cancer patients were 23.40%(3220/13760)，2.55%(351/13760) and 0.30%(41/13760)，respectively. Among the screening population，the 45～49 age group had the highest detection rate of suspected positive findings(27.79%，935/3365)，the 50~54 age group had the highest detection rate of positive findings(2.98%，97/3257)，and the 65～69 age group had the highest detection rate of breast cancer(0.49%，5/1012). The detection rate of breast cancer by ultrasound combined with mammography was 2.95%(316/10728)，which was significantly higher than that of breast ultrasound alone (1.99%，213/10728) or mammography alone(1.25%，134/10728). ［Conclusion］ Breast ultrasound combined with mammography for screening can significantly increase the detection rate of breast cancer. The compliance of participants，the program implementation and service capabilities of the screening provider need to be further improved. |
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