杨志杰,王 璐,钱 云.2015年江苏省前列腺癌发病与死亡及2006—2015年变化趋势分析[J].中国肿瘤,2020,29(11):838-843.
2015年江苏省前列腺癌发病与死亡及2006—2015年变化趋势分析
Incidence and Mortality of Prostate Cancer in Jiangsu Province in 2015 and the Trend of Changes During 2006—2015
中文关键词  修订日期:2020-05-12
DOI:10.11735/j.issn.1004-0242.2020.11.A009
中文关键词:  前列腺癌  发病率  死亡率  江苏
英文关键词:prostate neoplasms  incidence  mortality  Jiangsu
基金项目:无锡市医学重点学科(ZDXK010);无锡市医学重点人才(ZDRC004);无锡市青年医学人才(QNRC050、QNRC035);无锡市科技局项目(N20192041);无锡市卫健委重大项目(Z201905);无锡市卫健委青年项目(Q201944,Q201802);国家重点研发计划(2016YFC1302603);江苏省卫生计生委医学科研课题(H2017017)
作者单位
杨志杰 无锡市疾病预防控制中心 
王 璐 无锡市疾病预防控制中心 
钱 云 无锡市疾病预防控制中心 
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中文摘要:
      摘 要:[目的] 分析江苏省前列腺癌发病和死亡特征及其变化趋势,为制定前列腺癌的防控措施提供依据。[方法] 利用2015年江苏省肿瘤登记地区数据,计算前列腺癌分城乡、年龄别发病和死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、累积发病和死亡率(0~74岁)等指标。并结合2015年全省户籍人口数据,估计前列腺癌发病数和死亡数。利用Joinpoint软件,分析2006—2015年前列腺癌中标发病和死亡率的平均年度变化百分比(AAPC)。[结果] 2015年江苏省估计前列腺癌新发病例4603例,发病率为11.96/10万,中标率为6.33/10万,世标率为6.19/10万,累积发病率(0~74岁)为0.65%,约占全部恶性肿瘤发病的3.46%,居恶性肿瘤发病顺位第6位。估计因前列腺癌死亡病例2032例,死亡率为5.28/10万,中标率为2.60/10万,世标率为2.65/10万,累积死亡率(0~74岁)为0.19%,约占全部恶性肿瘤死亡的2.06%,位居恶性肿瘤死亡谱第9位。2006—2015年前列腺癌发病和死亡水平均呈明显上升趋势,其中发病中标率的AAPC为8.10%(95%Cl:5.60%~10.80%,P<0.05),死亡中标率AAPC为5.20%(95%Cl:3.20%~7.30%,P<0.05)。[结论] 江苏省前列腺癌的发病率和死亡率持续升高,已成为严重威胁江苏省男性健康的主要癌症之一,应在加强前列腺癌健康教育的同时,在重点人群尤其是城市60岁以上男性人群中开展早期筛查和干预。
英文摘要:
      Abstract:[Purpose] To analyze the incidence and mortality of prostate cancer in Jiangsu Province in 2015 and the trend of changes during 2006—2015.[Methods] The data of prostate cancer in Jiangsu cancer registration areas in 2015 were collected. The incidence and mortality of prostate cancer by urban and rural areas,age groups,and age-standardized incidence/mortality rates by Chinese standard population in 2000(ASIRC,ASMRC) and by Segi’s population(ASIRW,ASMRW),and cumulative incidence/mortality rates(0~74 years) were calculated. Joinpoint regression was performed to analyze the average annual percentage changes(AAPC) in ASIRC and ASMRC during 2006 to 2015. [Results] The estimated new cases of prostate cancer were 4603 in Jiangsu province in 2015,accounting for 3.46% of all cancer incidence and ranking the sixth. The crude incidence rate was 11.96/105,ASIRC and ASIRW were 6.33/105 and 6.19/105,respectively,and the cumulative incidence rate(0~74 years) was 0.65%.The estimated deaths of prostate cancer were 2032 in 2015,accounting for 2.06% of all cancer deaths and ranking the ninth. The crude mortality rate was 5.28/105,ASMRC and ASMRW were 2.60/105 and 2.65/105,respectively,and the cumulative mortality rate(0~74 years) was 0.19%.The AAPC of ASIRC was 8.1%(95%CI:5.6%~10.8%) and the AAPC of ASMRC was 5.2%(95%CI:3.2%~7.3%) from 2006 to 2015. [Conclusion] During 2006—2015,the incidence and mortality of prostate cancer presented sustained increasing trend in Jiangsu province. The early screening and intervention for prostate cancer,particularly for men over 60 years old in urban areas should be strengthened.
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