| 刘金辉,李琰琰,张 楠.山东省肥城市2013―2017年上消化道癌发病趋势分析[J].中国肿瘤,2020,29(5):361-366. |
| 山东省肥城市2013―2017年上消化道癌发病趋势分析 |
| ?壮rends of Upper Gastrointestinal Cancer Incidence from 2013 to 2017 in Feicheng，Shandong Province |
| 中文关键词 修订日期：2019-05-16 |
| DOI：10.11735/j.issn.1004-0242.2020.05.A007 |
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| 中文关键词: 上消化道癌 发病率 平均年度变化百分比 山东 |
| 英文关键词:upper gastrointestinal cancer,incidence average annual percentage changes Shandong |
| 基金项目:国家自然科学基金面上项目（81573246）；山东省科技发展计划项目（2017GSF18101）；国家重点研发计划项目（2016YFC1302800，2016YFC0901400）；山东省自然科学基金（ZR2019PG006）；山东省医学科学院院级科技计划项目（2018-05） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2013―2017年山东省肥城市上消化道癌（食管癌、胃癌）发病情况。［方法］ 分析肥城市肿瘤登记处积累的2013―2017年全部上消化道癌发病数据，利用Joinpoint软件计算粗发病率、中国标化率、世界标化率及其平均年度变化百分比(AAPC)，分析上消化道癌年龄别发病率变化趋势。［结果］ 5年间肥城市上消化道癌平均粗发病率为138.74/10万，占全部恶性肿瘤发病的49.84%，自50~54岁年龄组开始发病率增长趋势变快，75~79年龄组粗发病率达到高峰，上消化道癌总体粗发病率的AAPC为-4.7%（P<0.05），呈下降趋势。食管癌平均粗发病率为80.82/10万，粗发病率、中国标化率的AAPC分别为-5.7%、-9.5%，均呈现明显下降趋势（P<0.05）；胃癌平均粗发病率为57.94/10万，粗发病率、中国标化率的AAPC分别为-3.5%、-7.4%，发病率下降趋势均无统计学意义（P>0.05）。［结论］ 5年来肥城上消化道癌发病率有所下降，但仍在所有癌症发病中占较高比例，防控形势依然严峻，建议将50岁以上男性作为重点防控人群，结合肥城市上消化道癌筛查工作，加强癌症防治知识普及，控制危险因素从而降低上消化道恶性肿瘤的发病。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of upper gastrointestinal cancer incidence from 2013 to 2017 in Feicheng，Shandong province. ［Methods］ The accumulated data of upper gastrointestinal cancer from 2013 to 2017 were obtained from the Feicheng Cancer Registry. The crude incidence，Chinese standardized rate(ASR China)，world standardized rate(ASR world) and the average annual percentage changes(AAPC) were calculated by the Joinpoint software; and the incidence trend of upper gastrointestinal cancer by age was analyzed. ［Results］ From 2013 to 2017 the average crude incidence rate of upper gastrointestinal cancer in Feicheng was 138.74/105，accounting for 49.84% of all malignant tumors. The incidence rate has increased from the age group of 50～54 years，and reached the peak in the age group 75～79. The annual incidence showed a downward trend year by year，with AAPC of -4.7%（P<0.05）.The incidence of esophageal cancer was 80.82/105，the AAPC of the crude incidence，ASR China was -5.7% and -9.5% respectively(both P<0.05).The crude incidence of gastric cancer was 57.94/105，the AAPC of the crude incidence，ASR China was -3.5% and -7.4% respectively，but the incidence trend was not statistically significant（P>0.05）.［Conclusion］ The incidence of upper gastrointestinal cancer was decreased from 2013 to 2017，but it still accounts for a high proportion of all malignant tumors in Feicheng city. It is suggested to take males over 50 years old as the key population for prevention and control. |
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