| 雷海科,李小升,赵玉兰.2011―2018年重庆多中心恶性肿瘤出院患者生存分析[J].中国肿瘤,2020,29(3):192-198. |
| 2011―2018年重庆多中心恶性肿瘤出院患者生存分析 |
| Survival of Discharged Malignant Tumor Patients from Multi-centers in Chongqing from 2011 to 2018 |
| 中文关键词 修订日期：2019-04-15 |
| DOI：10.11735/j.issn.1004-0242.2020.03.A006 |
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| 中文关键词: 恶性肿瘤 随访 生存率 预后 重庆 出院患者 |
| 英文关键词:magligant tumour follow up survival rate prognosis Chongqing discharged patients |
| 基金项目:重庆市社会事业与民生保障科技创新专项（cstc2016shmszx13005）；重庆市技术创新与应用示范项目（cstc2018jscx-msybX0075） |
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| 中文摘要: |
| 摘 要：［目的］ 对重庆大学附属肿瘤医院牵头的8家医院2011至2018年出院的恶性肿瘤患者的生存情况进行统计分析。［方法］ 对所有恶性肿瘤患者进行随访，采用寿命表法计算主要恶性肿瘤的观察生存率。采用Log-rank检验比较不同年龄段、不同性别前10位恶性肿瘤的生存率。［结果］ 该次研究一共纳入60 088例恶性肿瘤患者，有效随访49 259例，有效随访率81.98%。主要恶性肿瘤患者１～５年生存率分别为76.55％、66.29％、59.88％、56.06％和52.97％。前10位恶性肿瘤患者中，5年生存率最高的是宫颈癌，达到90.70%，其次是乳腺癌，84.08%，生存率最低的是肝癌（14.66%），其次是肺癌（20.43%）；经Log-rank检验，不同恶性肿瘤的不同年龄段生存率差异均有统计学意义（P<0.05）；不同恶性肿瘤的不同性别生存率相差较大，其中不同性别的肺癌、继发性恶性肿瘤、胃癌差异有统计学意义（P<0.05），其他恶性肿瘤不同性别间的生存率差异均无统计学意义（P>0.05）。［结论］ 8家单位2011—2018出院的主要恶性肿瘤患者中，肝癌、肺癌、食管癌预后较差，宫颈癌、乳腺癌和鼻咽癌预后相对较好。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the survival of malignant tumor patients discharged from 8 hospitals in Chongqing from 2011 to 2018. ［Methods］ A total of 60 088 patients with malignant tumors discharged from 8 hospitals in Chongqing were included in the study, among whom 49 259 cases were effectively followed up with a follow-up rate of 81.98%. The survival rate was calculated by life table method. Log-rank test was used for testing differences of the survival rates of patients with different gender and age. ［Results］ The 1-, 2-, 3-, 4- and 5-year survival rates of patients with major malignant tumors were 76.55%, 66.29%, 59.88%, 56.06%, and 52.97% respectively. Among the patients with top 10 malignant tumors, cervical cancer had the highest 5-year survival rate (90.70%), followed by breast cancer (84.08%); and the liver cancer had the lowest survival rate (14.66%), followed by lung cancer (20.43%). Log-rank test showed that there were significant differences in survival of patients with different malignant tumors and in different age groups (P<0.05). There were significant differences in survival rates between male and female patients with lung cancer, secondary malignant tumor and gastric cancer (P<0.05). ［Conclusion］ Among the patients with main malignant tumor discharged from the 8 hospitals during 2011―2018, those with liver cancer, lung cancer and esophageal cancer had poorer prognosis, and those with cervical cancer, breast cancer and nasopharyngeal cancer hed relatively better prognosis. |
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