| 罗小虎,王 健,董 栋.城市癌症早诊早治项目肺癌高危风险评估模型在真实世界中的效果分析[J].中国肿瘤,2020,29(3):167-171. |
| 城市癌症早诊早治项目肺癌高危风险评估模型在真实世界中的效果分析 |
| Application of Lung Cancer Risk Assessment Model for Cancer Screening Program in Urban China |
| 中文关键词 修订日期：2019-08-26 |
| DOI：10.11735/j.issn.1004-0242.2020.03.A002 |
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| 中文关键词: 癌症筛查 风险评估 肺癌 模型 江苏 |
| 英文关键词:cancer screening high-risk assessment lung cancer model Jiangsu |
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| 中文摘要: |
| 摘 要：［目的］评估城市癌症早诊早治项目中肺癌高危风险预警模型评估效果，为建立适合中国人群的肺癌早诊早治模型提供理论基础。［方法］ 采取整群随机抽样的方法，于2014年1月至2018年12月选取徐州市区28个社区93 751人进行肺癌高危风险问卷调查及风险评估。评估为肺癌高危风险者将免费接受肺癌的临床筛查。［结果］肺癌高风险组肺癌发生的比率（0.42%，72/17193）高于非高风险组（0.17%，132/76558），差异有统计学意义（P<0.01）；分层分析发现：男性和女性、年龄＜50岁和≥50岁以及未参加LDCT筛查人群中，肺癌高风险组的肺癌发生比率均高于非高风险组，差异有统计学意义（P＜0.01）。高危预警模型在肺癌发病的预测中的敏感性为35.29%（72/204），特异性为81.70(76426/93547)。［结论］利用城市癌症筛查项目所建立的肺癌高危风险预警模型对发现高风险人群有一定作用。 |
| 英文摘要: |
| Abstract：［Purpose］ To evaluate the application of lung cancer risk assessment model for Cancer Screening Program in Urban China. ［Methods］ The random cluster sampling method was used to select 93 751 people from the 28 communities in Xuzhou city from January 2014 to December 2018，all subjects underwent questionnaire survey and the risk of lung cancer was assessed. Those who were assessed as high-risk of lung cancer would receive free clinical screening for lung cancer. ［Results］ The incidence rate of lung cancer in the high risk group(0.42%，72/17193) was higher than that in the non-high-risk group(0.17%，132/76558)（P<0.01）. The stratified analysis showed that the incidence rate of lung cancer in high-risk group of lung cancer was higher than that in the non-high-risk group both the males and females，those aged＜50 and aged≥50 years and the people who did not participate in low dose CT(LDCT) screening(all P＜0.01). The sensitivity of the risk assessment model of lung cancer was 35.29%(72/204) and the specificity was 81.70%(76426/93547). ［Conclusion］ The risk assessment model of lung cancer is of certain effectiveness for Cancer Screening Program in Urban China. |
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