| 张 艳,何 美,邱 惠.2015—2018年重庆市农村上消化道癌早诊早治项目内镜筛查结果分析[J].中国肿瘤,2020,29(3):161-166. |
| 2015—2018年重庆市农村上消化道癌早诊早治项目内镜筛查结果分析 |
| Endoscopic Screening for Upper Digestive Tract Cancer in Rural Areas of Chongqing，2015—2018 |
| 中文关键词 修订日期：2019-09-24 |
| DOI：10.11735/j.issn.1004-0242.2020.03.A001 |
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| 中文关键词: 上消化道癌 早诊早治 早期癌 内镜筛查 重庆 农村 |
| 英文关键词:upper gastrointestinal cancer early diagnosis and treatment early cancer endoscopic screening Chongqing rural areas |
| 基金项目:重庆市卫生计生委医学科研项目(2016ZDXM032)；国家重点研发计划精准医学研究重点专项(2016YFC0901400)；重庆市科学技术局科研机构绩效激励引导专项(cstc2018jxjl130058) |
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| 中文摘要: |
| 摘 要：［目的］ 分析总结2015—2018年重庆市农村地区上消化道癌（食管癌、贲门癌及胃癌）早诊早治项目内镜筛查结果。［方法］ 选择上消化道癌发病率较高的区县，采取整群抽样的方法，对8236例40~69岁的无症状的人群进行上消化道癌筛查。［结果］ 2015—2018年完成胃镜筛查8236例，活检2810例，共检出重度异型增生、高级别上皮内瘤变及癌71例，检出率为0.86%，其中食管重度异型增生及癌检出率为0.40%（33例），贲门高级别上皮内瘤变及癌检出率为0.15%（12例），胃高级别上皮内瘤变及癌检出率为0.32%（26例）；其中早期病例59例，早诊率为83.10%；治疗病例62例，治疗率87.32%。对未治疗的癌前病变以上患者共348例进行随访，成功随访228例，随访率为65.52%，其中随访中新发现病例5例，全为早期病例，并已全部接受治疗。［结论］ 开展上消化道癌筛查，不仅普及了当地群众的肿瘤防治知识，还能及时发现癌前病变及早期癌，并通过适宜的干预手段从而阻断疾病的进行性发展，降低癌症的发病率和死亡率，同时，提高了基层医疗单位及工作人员的癌症防控水平。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of endoscopic screening for upper digestive cancer(esophageal cancer，cardiac cancer and gastric cancer) in rural areas of Chongqing from 2015 to 2018. ［Methods］ In districts and counties with high incidence of upper digestive tract cancer，8236 asymptomatic people aged 40～69 years were selected for screening of upper digestive tract cancer by cluster sampling. ［Results］ Total 8236 participants underwent gastroscopic screening and 2810 cases of biopsy were performed. A total of 71 cases of severe dysplasia，high-grade intraepithelial neoplasia(HGIEN) and cancer were detected with a detection rate of 0.86%，among which the detection rate of esophageal severe dysplasia and cancer was 0.40%(33 cases)，the detection rate of cardiac HGIEN and cancer was 0.15%(12 cases)，and the detection rate of gastric HGIEN and cancer was 0.32%(26 cases). Among 71 detected cases there were 59 early cases with an early diagnosis rate of 83.10%；62 cases were treated with a treatment rate of 87.32%. Among 348 patients with precancerous lesions，228 were followed up with a follow-up rate of 65.52%；and 5 new cases were discovered during the follow-up，all of whom were early cases and received appropriate treatment. ［Conclusion］ Screening for upper digestive cancer can detect precancerous lesions and early cancer in time，and block the progression of the disease through appropriate interventions，which would reduce the cancer morbidity and mortality. |
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