| 罗卫平,张 琳,唐怡菁.上海市奉贤区2014—2016年社区居民大肠癌筛查结果分析[J].中国肿瘤,2020,29(2):108-113. |
| 上海市奉贤区2014—2016年社区居民大肠癌筛查结果分析 |
| Analysis on the Result of Colorectal Cancer Screening in Community?鄄based Residents of Fengxian District during 2014 to 2016 in Shanghai |
| 中文关键词 修订日期：2019-09-29 |
| DOI：10.11735/j.issn.1004-0242.2020.02.A005 |
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| 中文关键词: 结直肠癌 筛查 依从率 早诊早治 社区居民 上海 |
| 英文关键词:colorectal cancer screening compliance early diagnosis and treatment community residents Shanghai |
| 基金项目:上海市重大公共卫生服务项目（2011）；上海市政府实事项目（2016）；上海市奉贤区政府实事项目（2015） |
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| 中文摘要: |
| 摘 要：［目的］ 分析上海市奉贤区第二轮社区居民大肠癌筛查项目的效果。［方法］ 对2014—2016年上海市奉贤区常住居民进行第二轮大肠癌筛查，采用危险度评估问卷调查结合大便隐血试验（FOBT）的筛查模式，初筛阳性者建议全结肠镜检查，并对结果进行分析。［结果］ 3年内共计完成初筛63 156人，初筛阳性率31.58%，男性和女性 60~岁组和70~岁组人群初筛阳性率均为最高；肠镜检查依从率为45.25%，男性肠镜检查依从率显著高于女性（χ2=7.44，P＜0.05），且80~岁年龄组的肠镜检查依从率最低；总病变检出率19.40%，总病变检出率随着年龄增长呈上升的趋势（χ2=32.86，P＜0.05），且男性显著高于女性，差异有统计学意义（χ2=152.94，P＜0.05）；单一评估阳性组的肠镜检查依从率、总病变检出率、癌及癌前病变检出率分别为39.55%、16.58%和7.48%，均低于单一大便隐血试验（FOBT）阳性组（分别为46.26%、20.80%和10.46%），差异均有统计学意义（χ2分别为132.00、15.97和14.34，P均＜0.05）；9025例肠镜检查共检出大肠癌147例，早期比例为39.25%。［结论］大肠癌筛查项目通过初筛和全结肠镜检查，显著提高大肠癌早期及癌前病变的检出率，对于降低大肠癌的死亡率和延长生存时间具有重要意义。由于奉贤区组织发动工作到位，肠镜检查依从率高于其他城区。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of the second-round screening colorectal cancer program among community residents of Fengxian district of Shanghai．［Methods］ The permanent community residents in Fengxian district were invited to take part in the second screening program of colorectal cancer from 2014 to 2016. They were screened through using the quantitative assessment questionnaire of risk factors and fecal occult blood tests(FOBT).The residents with the positive screening test results were suggested to take colonoscopy test and the results were analyzed.［Results］ A total of 63 156 community residents were screened within 3 years，with a screening positive rate of 31.58%. The 60~ age group and 70~ age group had the highest screening positive rates regardless of their gender. The compliance rate of colonoscopy was 45.25%. The compliance rate of colonoscopy in male was significantly higher than that in female（χ2=7.44，P＜0.05）， and the compliance rate of colonoscopy was the lowest in the high age group(80~). The overall detection rate of lesion was 19.40%，which increased with the age（χ2=32.86，P＜0.05） and was much higher among male with a statistically difference（χ2=152.94，P＜0.05）. The compliance rate of colonoscopy，detection rate of lesion and detection rate of cancer in questionnaire group were 39.55%，16.58% and 7.48% respectively，which were lower than those among FOBT group（46.26%，20.80% and 10.46% respectively） and had a statistically difference（χ2=132.00，15.97 and 14.34，P＜0.05 in all）. Among 9025 colonoscopies，147 cases of colorectal cancer were detected，and 39.25% of them were at early stage. ［Conclusion］ The colorectal cancer screening program can significantly improve the detection rate of early colorectal cancer and precancerous lesions through primary screening and colonoscopy，which is of great significance for reducing the mortality rate of colorectal cancer and prolonging the survival time. The compliance rate of colonoscopy in Fengxian district was higher than other urban areas due to their excellent organization. |
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