| 许 欢,李 科,梁颖茹.2004—2016年广州市膀胱癌发病情况及其趋势分析[J].中国肿瘤,2019,28(12):913-917. |
| 2004—2016年广州市膀胱癌发病情况及其趋势分析 |
| Analysis on Incidence of Bladder Cancer in Guangzhou City and Its Trend from 2004 to 2016 |
| 中文关键词 修订日期：2019-08-02 |
| DOI：10.11735/j.issn.1004-0242.2019.12.A006 |
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| 中文关键词: 膀胱癌 发病率 趋势 广东 |
| 英文关键词:bladder cancer incidence trend Guangdong |
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| 中文摘要: |
| 摘 要：［目的］ 分析广州市2004—2016年膀胱癌发病情况及其趋势。［方法］ 根据广州市肿瘤登记处收集的2004—2016年广州市膀胱癌病例数据，分析粗发病率、年龄别发病率、2000年中国人口标化发病率（中标率）、Segi’s世界人口标化发病率（世标率）、35~64岁截缩率、0~64岁累积发病率、0~74岁累积发病率、年均变化百分比（APC）。［结果］ 广州市2016年户籍居民膀胱癌新发病例502例，男、女世标发病率之比为3.88∶1（男性5.43/10万，女性1.40/10万），男、女世标发病率均呈平稳下降趋势（男性APC=-2.68%，95%CI：-3.7%~-1.6%，P＜0.05；女性APC=-3.30%，95%CI：-4.80%~-1.70%，P＜0.05）。城区、郊区和郊县世标发病率之比为1.51∶1.50∶1（城区3.44/10万，郊区3.42/10万，郊县2.28/10万），城区世标发病率呈明显下降趋势（APC=-5.25%，95%CI：-6.4%~-4.1%，P＜0.05），郊区下降趋势无统计学意义(APC=-0.76%，95%CI：-2.6%~1.1%，P＞0.05)，郊县呈明显增长趋势（APC=6.15%，95%CI：2.2%~10.2%，P＜0.05）。男、女性膀胱癌发病均从50岁开始快速上升，男性在85岁以上年龄组达到发病高峰（97.50/10万），女性在80~85岁年龄组达到发病高峰（30.30/10万）。［结论］ 广州市膀胱癌男性发病率明显高于女性，城郊发病差距逐渐缩小，应加强对50岁以上男性高危人群，尤其是郊县地区男性膀胱癌的有效防治。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and its trend of bladder cancer in Guangzhou from 2004 to 2016.［Methods］ The data from Guangzhou Cancer Registry during 2004—2016 were collected to calculate the incidence of bladder cancer，age-specific incidence rate，age-standardized rate by China population 2000(ASR-C) and by Segi’s world standard population(ASR-W)，truncated age-standardized rate by Segi’s world standard population，cumulative rate and annual percent change(APC). ［Results］ There were a total of 502 cases diagnosed as bladder cancer in 2016. The gender ratio of ASR-W was 3.88∶1(5.43/105 in male，1.40/105 in female). The ASR-W of bladder cancer had a stable downward trend in male(APC=-2.68%，95%CI：-3.7%~-1.6%，P＜0.05) and female(APC=-3.30%，95%CI：-4.80%~-1.70%，P＜0.05). The area ratio of ASR-W was 1.51∶1.50∶1(3.44/105 in urban，3.42/105 in suburb，2.28/105 in county). The ASR-W of bladder cancer in urban(APC=-5.25%，95%CI：-6.4%~ -4.1%，P＜0.05) had an obvious downward trend. There was no change observed in suburb(APC=-0.76%，95%CI：-2.6%~1.1%，P＞0.05).The ASR-W of bladder cancer in county(APC=6.15%，95%CI：2.2%~10.2%，P＜0.05) had an obvious upward trend. The incidence in male and female increased rapidly after 50 years old，and peaked at the age group of over 85 years old(97.50/105) in male and 80~84 years old(30.30/105) in female. ［Conclusion］ The incidence of bladder cancer is higher in male than that in female in Guangzhou City. The ASR-W gap was increasingly small between urban and country areas. We should focus on strengthening the prevention and control on bladder cancer in high risk group of male(>50 years old)，especially in county areas. |
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