冯 祥,华召来,魏文强.江苏省扬中市居民上消化道癌及癌前病变筛查结果及影响因素分析[J].中国肿瘤,2019,28(12):901-906.
江苏省扬中市居民上消化道癌及癌前病变筛查结果及影响因素分析
Screening of Upper Gastrointestinal Cancer and Precancerous Lesions in Yangzhong City of Jiangsu Province
中文关键词  修订日期:2019-04-19
DOI:10.11735/j.issn.1004-0242.2019.12.A004
中文关键词:  上消化肿瘤  癌前病变  筛查  影响因素  江苏
英文关键词:upper gastrointestinal neoplasms  precancerous lesions  screening  influencing factors  Jiangsu
基金项目:国家重点研发计划(2016YFC0901400);“十一五”国家科技支撑计划(2006BAl02A15)
作者单位
冯 祥 扬中市肿瘤防治研究所 
华召来 扬中市肿瘤防治研究所 
魏文强 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院 
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中文摘要:
      摘 要:[目的]了解扬中市居民上消化道癌及癌前病变的检出情况,探讨其影响因素。[方法]采用整群抽样的方法确定调查对象。采用问卷调查、体格检查、内窥镜检查和病理学检查对调查对象进行上消化道癌及癌前病变的筛查。[结果]筛查总人数2591人,共检出阳性病例228例,检出率8.80%,其中男性128例(11.24%),女性100例(6.89%),差异有统计学意义(P<0.001)。多因素Logistic回归分析显示,年龄(50~岁:OR=2.948,95%CI:1.671~5.199;60~岁:OR=7.846,95%CI:4.538~13.567),吸烟(OR=1.738,95%CI:1.301~2.321),深度油炸食品(OR=2.549,95%CI:1.223~5.311),幽门螺旋杆菌(OR=1.585,95%CI:1.194~2.103)是上消化道癌及癌前病变的独立影响因素。[结论]年龄大、吸烟、经常食用深度油炸食品、感染幽门螺旋杆菌是扬中市居民患上消化道癌及癌前病变的危险因素。
英文摘要:
      Abstract:[Purpose] To analyze the results of screening for upper gastrointestinal cancer and precancerous lesions in Yangzhong City. [Methods] A screening program for gastrointestinal cancer and precancerous lesions was conducted in 2 townships of Jiangsu Yangzhong City in 2018;participants were selected by cluster sampling method. The subjects were screened by using questionnaires,physical examination,endoscopy and pathology. [Results] Two hundred and twenty-eight of 2591 participants were positive in screening with a detection rate of 8.80%. The detection rate of males and females was 11.24% and 6.89%,respectively(P<0.001). Multivariate logistic regression analysis showed that the age(50~:OR=2.948,95%CI:1.671~5.199;60~:OR=7.846,95%CI:4.538~13.567),smoking(OR=1.738,95%CI:1.301~2.321),deep-fried food(OR=2.549,95%CI:1.223~5.311) and Helicobacter pylori(Hp) infection(OR=1.585,95%CI:1.194~2.103) were risk factors of upper gastrointestinal cancer and precancerous. [Conclusion] Older age,smoking,deep-fried food,and Helicobacter pylori infection may increase the risk of upper gastrointestinal cancer and precancerous lesions.
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