| 肖海帆,颜仕鹏,许可葵.湖南省2012—2018年城市癌症早诊早治项目临床筛查结果初步分析[J].中国肿瘤,2019,28(11):807-815. |
| 湖南省2012—2018年城市癌症早诊早治项目临床筛查结果初步分析 |
| Analysis of Cancer Screening Program in Changsha Urban Area from 2012 to 2018 |
| 投稿时间：2019-02-28 |
| DOI：10.11735/j.issn.1004-0242.2019.11.A002 |
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| 中文关键词: 癌症 早诊早治 临床筛查 风险评估 城市 湖南 |
| 英文关键词:cancer early diagnosis and treatment：clinical screening risk assessment urban Hunan |
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| 中文摘要: |
| 摘 要：［目的］ 分析湖南省2012年至2018年城市癌症早诊早治项目中高危人群评估、临床筛查和阳性检出率，为开展癌症防控工作提供依据。［方法］ 在长沙市5个城区，动员所有40～74岁常住户籍居民填写高危风险评估问卷，检出的高危者接受肺癌、乳腺癌、上消化道癌、结直肠癌和肝癌临床筛查，分析评估各癌种各年的高风险率和临床筛查阳性检出率。［结果］ 2012年至2018年完成高危人群评估共293 760人，肺癌、乳腺癌、上消化道癌、结直肠癌和肝癌的高危风险率分别为19.12%、19.45%、12.05%、13.31%、和12.32%。完成临床筛查72 673人次，共检出可疑癌症/癌症603例，检出率为0.83%，其中检出可疑肺癌207例（检出率为0.89%），可疑乳腺癌322例（检出率为2.21%），可疑肝癌35例（检出率为0.21%），确诊结直肠癌28例（检出率为0.35%），确诊上消化道癌11例（检出率为0.11%）。共检出其他阳性病例6407例，检出率为8.81%。其中检出阳性肺结节1368例（检出率为5.92%），乳腺BI?鄄RADS 3类2933例（检出率为20.13%），肝硬化及肝脏占位性病变104例（检出率为0.62%），确诊结直肠癌癌前病变1170例（检出率为14.47%），确诊上消化道癌前病变859例（检出率为8.65%）。［结论］对五大癌症的高危人群进行临床筛查，能够有效降低筛查成本和提高癌症阳性检出率，从而降低癌症发病率和死亡率。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the preliminary results of cancer screening program in urban area of Changsha city from 2012 to 2018. ［Methods］ In five urban areas of Changsha city，permanent residents in Changsha urban area aged between 40 and 74 years were invited to participate in the cancer screening program. The risks for lung cancer，breast cancer，upper digestive tract cancer，colorectal cancer and liver cancer were assessed by questionnaire survey，and the identified high-risk subjects underwent the further clinical screening. The screening results were evaluated. ［Results］ From 2012 to 2018，a total 293 760 participated in the program，and the risk rates of lung cancer，breast cancer，upper gastrointestinal cancer，colorectal cancer and liver cancer were 19.12%，19.45%，12.05%，13.31%，12.32%，respectively. There were 72 673 person-time of clinical screening completed，and 603 cases of suspicious or diagnosed cancer were detected with a cancer detection rate of 0.83%，among whom there were 207 cases of suspicious lung cancer(0.89%)，322 cases of suspected breast cancer(2.21%)，35 cases of suspected liver cancer(0.21%)，28 cases of diagnosed colorectal cancer(0.35%) and 11 cases of diagnosed upper gastrointestinal carcinoma. There were 6407 cases of other positive conditions detected，among whom there were 1368 cases of positive pulmonary nodules(5.92%)，2933 cases of breast BI-RADS 3(20.13%)，104 cases of liver cirrhosis and liver occupying lesions(0.62%)，1170 cases of precancerous colorectal lesions(14.47%)，and 859 cases of precancerous upper gastrointestinal lesions(8.65%). ［Conclusion］ Clinical screening for the high-risk population of the five major cancers may improve the positive detection rate of cancer，and reduce the screening cost. |
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