| 查震球,贾尚春,陈叶纪.2015—2018年安徽省癌症早诊早治项目农村地区肝癌筛查分析[J].中国肿瘤,2019,28(10):743-748. |
| 2015—2018年安徽省癌症早诊早治项目农村地区肝癌筛查分析 |
| Results of Liver Cancer Screening in Rural Areas of Anhui Province from 2015 to 2018 |
| 投稿时间：2019-09-16 |
| DOI：10.11735/j.issn.1004-0242.2019.10.A005 |
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| 中文关键词: 肝癌 筛查 乙肝表面抗原 农村地区 安徽 |
| 英文关键词:liver cancer screening hepatitis B surface antigen rural areas Anhui |
| 基金项目:协同创新 中国医学科学院医学与健康科技创新工程(2019?鄄I2M?鄄2?鄄004) |
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| 中文摘要: |
| 摘 要：［目的］ 分析2015—2018年安徽省癌症早诊早治项目肝癌筛查结果。［方法］ 对安徽省农村常住居民（35～64 岁男性和 45～64岁女性）采用问卷调查评估出肝癌高危人群；经知情同意后进行肝脏B超检查及甲胎蛋白 (AFP)检测，并对筛查结果进行分析。［结果］ 共有177 586名目标人群完成流行病学危险因素调查，处于高危风险的有45 893人，高风险率为25.78%。乙肝表面抗原（HbsAg）阳性为11 295人，阳性率为6.36%。对27 794人进行了临床诊断性检查，共检出182例肝癌患者，检出率为0.65%。 ［结论］ 宿州市埇桥区等6个地区的肝癌患病风险和检出率较高，有消化系统疾病史人群的HbsAg阳性检出率较高。高危人群进行临床筛查的依从性较低，需要进一步提高居民对癌症早诊早治的认识，完善肝癌筛查机制，从而实现肝癌患者的早发现、早治疗。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of liver cancer screening in rural area of Anhui province from 2015 to 2018.［Methods］ The liver cancer screening program was conducted among rural residents(35~64 years of age for male and 45～64 years for female) in Anhui province from 2015 to 2018. The risk of liver cancer was assessed by questionnaire survey in all subjects，and the liver ultrasonography and alpha-fetoprotein(AFP) test were performed for identified high-risk subjects. ［Results］ The risk assessment was performed in 177 586 participants and 45 893 subjects were id-entified as high risk of liver cancer(25.78%). The HbsAg positive rate was 6.36%(11295/177586). Among 45 893 high-risk subjects，the clinical diagnostic examination was performed in 27 794 subjects，and 182 case of liver cancer was detected with a detection rate of 0.65%(182/27794). ［Conclusion］ The results shows that the compliance of clinical examination in high-risk subjects is low，indicating that it is necessary to further improve residents’ awareness of early diagnosis and treatment of liver cancer. |
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