| 马恒敏,史思达,陈万青.山东省2007—2015年度鲁西南地区五县市农村人群食管癌筛查分析[J].中国肿瘤,2019,28(10):738-742. |
| 山东省2007—2015年度鲁西南地区五县市农村人群食管癌筛查分析 |
| Esophageal Cancer Screening in Five Counties of Southwest Shandong Province from 2007 to 2015 |
| 投稿时间：2019-09-08 |
| DOI：10.11735/j.issn.1004-0242.2019.10.A004 |
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| 中文关键词: 食管癌 癌前病变 筛查 早诊早治 农村地区 山东 |
| 英文关键词:esophageal cancer precancerous lesions screening early diagnosis and treatment rural areas Shandong |
| 基金项目:科技部国家重点研发计划 (2018YFC1313100 )；公益性行业科研专项(201502001)；国家自然科学基金（8157120974）；山东省科技发展计划项目（2017GSF18101） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2007—2015年度山东省鲁西南地区五县市（济宁汶上县、枣庄滕州市、济宁梁山县、菏泽牡丹区、菏泽单县）农村地区人群食管癌内镜筛查结果，为山东省农村地区食管癌防治提供科学依据。［方法］ 采用整群随机抽样选取山东省鲁西南地区五县市40～69岁人群，对其进行高危因素调查、内镜碘染色筛查及病理诊断。计算阳性病例检出率、早诊率、治疗率等指标。［结果］ 2007—2015年度共完成内镜筛查41 068人，确诊食管阳性病例217例，其中早期病例165例，治疗190例，病例检出率、早诊率、治疗率分别为0.53%、76.04%、87.56%；男性食管各级病变的检出率明显高于女性（P<0.05），各级病变的检出率均随着受检者年龄的增长而增加（P<0.05）。［结论］ 山东省鲁西南地区五县市食管癌内镜筛查效果良好，但仍需进一步提高筛查效果，其中提高活检率是重点。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the endoscopic screening results of esophageal cancer in rural areas of five counties(Wenshang，Tengzhou，Liangshan，Mudan District，Shanxian) in Shandong province from 2007 to 2015. ［Methods］ In five counties，a questionnaire-based survey，endoscopic iodine staining screening and pathological diagnosis were conducted among residents aged 40～69 years old who were selected by random cluster sampling method. The detection rate of positive cases，diagnosis rate of early cancer，rate of treatment and other indicators were calculated. ［Results］ A total of 41 068 cases completed the endoscopic screening from 2007 to 2015，and 217 positive cases were detected，including 152 cases of sever dysplasia/carcinoma in situ，13 cases of early esophageal cancer and 52 cases of invasive esophageal cancer. The detection rate，early diagnosis rate and treatment rate were 0.53%(217/41068)，76.04%(165/217) and 87.56%(190/217)，respectively. The detection rate of esophageal lesions in males was significantly higher than that in females(P<0.05)，and the detection rate of lesions increased with the age of the screening subjects(P<0.05). ［Conclusion］ Although the endoscopic screening had good effect in rural areas of five counties in southwest Shandong，the effect still needs to be further improved，and the key point is to increase the biopsy rate. |
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