| 陈媛媛,董百强.体部立体定向放疗在肺部肿瘤中的应用[J].中国肿瘤,2018,27(6):454-459. |
| 体部立体定向放疗在肺部肿瘤中的应用 |
| Application of Stereotactic Body Radiotherapy(SBRT) in Lung Cancer |
| 投稿时间：2018-01-29 |
| DOI：10.11735/j.issn.1004-0242.2018.06.A010 |
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| 中文关键词: 体部立体定向放射治疗 非小细胞肺癌 肺转移癌 |
| 英文关键词:stereotactic body radiotherapy non-small cell lung cancer lung metastases |
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| 中文摘要: |
| 摘 要：体部立体定向放疗(stereotactic body radiotherapy，SBRT)是将放射剂量聚集到病灶，几次照射（≤5次）即可达到根治剂量，用立体准确定向的高能射线来杀灭肿瘤。精确定位、精准制导以及严密质控，使高剂量消融肿瘤的同时，危及器官得到保护，也使得SBRT应用更加广泛。老龄化提前到来和低剂量螺旋CT的普及使得早期肺癌的确诊明显增加；因内科基础疾病或多原发而不能手术的肺部病灶，SBRT可提供很高的局部控制率；对可手术病灶，SBRT能达到相似的局部控制率；另外对肺孤立转移瘤，全身联合局部治疗已被普遍接受。全文对SBRT在肺部肿瘤中的研究进展作一综述。 |
| 英文摘要: |
| Abstract：In stereotactic body radiotherapy(SBRT)，radical dose of high-energy rays is delivered to lesions in a few(≤5) fractions. Tight quality control allows ablation of tumors with high-dose radiation while preserving the organs at risk (OAR)，making SBRT widely applicable. The aging of the population and common use of low-dose helical CT may increase the early diagnosis rate of lung cancer. SBRT provides an encouraging rate of local control for patients with either unresectable or resectable lesions；as for patients with isolated lung metastases，systemic treatment combined with local treatment has been widely applied. This paper reviews the research progress of SBRT in lung cancer. |
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