| 宋方彬,徐军明,姚 武.乳腺癌内分泌治疗预测因素的研究进展[J].中国肿瘤,2017,26(12):977-981. |
| 乳腺癌内分泌治疗预测因素的研究进展 |
| Research Progress on Predictive Factors for Endocrine Therapy in Breast Cancer |
| 投稿时间：2017-04-20 |
| DOI：10.11735/j.issn.1004-0242.2017.12.A010 |
|
 |
| 中文关键词: 乳腺肿瘤 内分泌治疗 内分泌耐药 基因测定 液态活检 |
| 英文关键词:breast neoplasms endocrine therapy endocrine resistance gene testing liquid biopsy |
| 基金项目: |
|
| 摘要点击次数: 1702 |
| 全文下载次数: 438 |
| 中文摘要: |
| 摘 要：内分泌治疗是雌激素受体（ER）阳性乳腺癌治疗的重要手段之一。临床研究显示，许多接受内分泌治疗的患者在治疗期间或治疗后发生复发，这些患者对内分泌治疗原发耐药或在治疗期间发生耐药。因此，有必要寻找可靠预测因子来预测哪些患者对内分泌治疗敏感。本文主要探讨临床病理因素、多基因检测及液体活检在乳腺癌内分泌治疗中的预测作用。 |
| 英文摘要: |
| Abstract：Endocrine therapy(ET) is an important treatment for ER-positive breast cancer. The clinical studies have shown that patients may relapse during or following completion of adjuvant ET，and have primary resistance or develop resistance to ET during treatment，so reliable indicators are needed for patients to predict the respond to ET. This article reviews the main research progress on predictive roles of clinicopathologic parameters，multigene tests and liquid biopsy in response to ET for patients with breast cancer. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |