| 李艳华,卢玉强,凌 伟.广东省四会市1987~2009年恶性肿瘤生存率分析[J].中国肿瘤,2017,26(8):596-600. |
| 广东省四会市1987~2009年恶性肿瘤生存率分析 |
| Survival Analysis of Patients with Malignant Tumors in Sihui City Between 1987 and 2009 |
| 投稿时间：2016-11-23 |
| DOI：10.11735/j.issn.1004-0242.2017.08.A003 |
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| 中文关键词: 肿瘤 生存率 广东 |
| 英文关键词:tumor survival rate Guangdong |
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| 中文摘要: |
| 摘 要：［目的］ 分析广东省四会市1987~2009年主要恶性肿瘤患者的生存状况，为肿瘤的预后评价和防控提供科学依据。［方法］ 收集并整理1987~2009年四会市全人群肿瘤登记数据共11 456例，随访截止日期为2014年12月31日。用Log-rank检验对各年龄组、性别组和各主要癌症不同确诊年份段的生存率进行比较。采用Cox回归模型进行多因素分析。［结果］ 23年间，四会市鼻咽癌、胃癌、结直肠癌、乳腺癌、肝癌、肺癌、宫颈癌、子宫体癌、甲状腺癌9种恶性肿瘤的5年OS有明显提高，差异有统计学意义（P<0.05）；而食道癌、膀胱癌、淋巴瘤、白血病的5年生存率在这3个年份阶段中的变化无统计学差异。各确诊年份段的女性生存率均高于男性，女性死亡风险是男性的0.77倍；≥70岁年龄组的死亡风险是<40岁组的2.23倍；2007~2009年的死亡风险是1987~1996年的0.71倍。［结论］ 23年来，四会市全人群恶性肿瘤生存率有所提高，但与国外发达国家及国内其他地区比较仍处于较低水平，提示应重视其他主要癌症的早诊早治工作。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the survival of malignant tumor patients in Sihui city from 1987 to 2009. ［Methods］ Data of 11456 cancer patients diagnosed between 1987 and 2009 were collected from Sihui cancer registration. Patients were followed up until December 31，2014. Survival diffe-rences among patients with different age，sex and year at diagnosis were analyzed by Log-rank test. Multivariable Cox proportional hazards model was applied for evaluation of the related factors to survival outcome. ［Results］ The 5-year overall survival(OS) of nasopharyngeal，colorectal，breast，liver，lung，cervical，uterine and thyroid cancers was significantly improved over the past twenty-three years，whereas no significant difference was observed for esophageal cancer，prostate cancer，lymphoma and leukemia. After adjustment，cancer survivals were significantly higher in females than those in males. The ratio of excess hazard of death between females and males was 0.77. Higher age group had higher survival rates than lower age group，the excess hazard of death in patients aged over 70 years was 1.23 times higher than that in those aged lower than 40 years. The ratio of excess hazard of death between patients diagnosed at 2007~2009 and those diagnosed at 1987~1996 was 0.71. ［Conclusion］ The cancer survivals have been improved in Sihui，however，compared with that in other regions in China and in developed countries，the survivals are still low. |
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