| 杨 锐,张旭辉.多层螺旋CT灌注扫描技术在肾脏原发性神经内分泌肿瘤中的诊断价值[J].中国肿瘤,2017,26(7):574-577. |
| 多层螺旋CT灌注扫描技术在肾脏原发性神经内分泌肿瘤中的诊断价值 |
| Diagnosis Value of Multi-slice Spiral CT Perfusion Imaging for Primary Renal Neuroendocrine Neoplasms |
| 投稿时间：2016-07-14 |
| DOI：10.11735/j.issn.1004-0242.2017.07.A014 |
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| 中文关键词: 多层螺旋CT灌注扫描 肾脏肿瘤 神经内分泌肿瘤 诊断 |
| 英文关键词:multi slice spiral CT perfusion scan renal neoplasms neuroendocrine neoplasm diagnosis |
| 基金项目:十堰市科学技术研究与开发项目（2014-14Y52） |
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| 中文摘要: |
| 摘 要：［目的］ 研究多层螺旋CT灌注(MSCTPI)扫描技术在肾脏原发性神经内分泌肿瘤（NEN）诊断中的临床价值。［方法］ 研究对象选取2014年5月至2016年1月间经病理学检查确诊为肾脏原发性NEN患者42例和肾错构瘤患者44例，同期选取45名健康志愿者作为对照组，采用多层螺旋CT对所有受试者肾皮质进行灌注扫描，分别计算各组的血流(BF)、相对组织血容量(rBV)、峰值时间(TTP)、峰值增强影像(PEI)、表面通透性(PS)、平均通过时间(MTT)和灌注(Perfusion)。［结果］ 肾脏NEN组的BF、BV值均高于肾错构瘤组和对照组(P<0.05)，肾脏NEN组和肾错构瘤组的PS值均明显低于对照组(P<0.05)。肾脏NEN组的rBV、PEI及Perfusion值明显高于肾错构瘤组(P<0.05)，但TTP值明显低于肾错构瘤组(P<0.01)；肾脏NEN组的rBV和TTP值明显高于对照组(P<0.05)，但Perfusion和PEI值明显低于对照组(P<0.05)。［结论］ 应用多层螺旋CT灌注扫描技术诊断肾脏原发性NEN，能够较好反映与正常组织和良性肿瘤之间的血流动力学指标差异，较好地鉴别肾脏良恶性肿瘤。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the diagnosis value of multi-slice spiral CT perfusion imaging in primary renal neuroendocrine neoplasm(NEN). ［Methods］ Forty-two patients with primary renal NEN(renal NEN group) and 44 cases with renal hamartoma(renal hamartoma group) proved pathologically were enrolled in this study form May 2014 to January 2016，and 45 healthy volunteers were selected as control group at the same period. Renal cortical perfusion scan with multi-slice spiral CT were performed in all subjects. Blood flow(BF)，relative blood volume(rBV)，time to peak(TTP)，peak enhancement image(PEI)，permeability surface(PS)，mean transit time(MTT) and perfusion were calculated. ［Results］ The BF，BV value in renal NEN group was higher than that in renal hamartoma group and control group(P<0.01). The PS value in renal NEN group and renal hamartoma group was significantly lower than that in control group(P<0.01). The rBV，PEI and perfusion value in renal NEN group was significantly higher than that in renal hamartoma group(P<0.01)，but TTP value was significantly lower than that in renal hamartoma group(P<0.01). The rBV and TTP values were significantly higher than that in control group(P<0.01)，but perfusion and PEI value was significantly lower than that in control group(P<0.01). ［Conclusion］ Multi-slice spiral CT perfusion imaging can differentiate renal NEN with normal tissue and benign better in hemodynamic parameters，and identificate benign and malignant tumors better. |
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