何英丽,张文杰,刘玉琴.2011~2015年甘肃省高台县上消化道癌早诊早治项目内镜筛查结果分析[J].中国肿瘤,2017,26(6):447-451.
2011~2015年甘肃省高台县上消化道癌早诊早治项目内镜筛查结果分析
Analysis of Endoscopic Screening for Upper Digestive Tract Cancer in Gaotai County,2011~2015
投稿时间:2016-10-19  
DOI:10.11735/j.issn.1004-0242.2017.06.A007
中文关键词:  消化道癌  内镜筛查  食管肿瘤  贲门癌  胃肿瘤  甘肃
英文关键词:upper gastrointestinal cancer  endoscopic screening  esophagus neoplasms  cardia cancer  gastric neoplasms  Gansu
基金项目:
作者单位
何英丽 甘肃省高台县人民医院 
张文杰 兰州大学第二医院 
刘玉琴 甘肃省肿瘤医院肿瘤流行病研究中心 
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中文摘要:
      摘 要:[目的] 总结分析5838例无症状人群上消化道癌内镜筛查结果。[方法] 将高台县40~69岁的高危人群设定为上消化道癌筛查人群,采用整群抽样法进行抽样。对筛查人群进行内镜检查+碘染色及指示性活检,并对筛查结果进行统计分析。[结果] 2011~2015年完成胃镜筛查病例5838例,共检出高级别上皮内瘤变及癌140例,检出率为2.40%,其中食管癌检出率为0.98%(57例),贲门癌为0.57%(33例),胃癌(非贲门)为0.86%(50例)。早期病例94例,早诊率为67.14%。应随访例数162例,实际随访105例,随访率为63.64%。随访中新发现病例6例,6例全部为早期病例,随即全部进行治疗。随访早诊率为100%,随访治疗率为100%。[结论] 内镜检查+碘染色加指示性活检能有效发现可干预的癌前病变及早期癌。提高筛查项目点团队的专业技术能力,加强对高危人群的随访、治疗以及癌症防治知识的宣传,是开展上消化道癌症早诊早治项目的关键。
英文摘要:
      Abstract:[Purpose] To analyze the results of endoscopy screening for upper digestive cancer in Gaotai county of Gansu province. [Methods] Total 5838 subjects aged 40 to 69 years were selected by cluster sampling method for screening of upper digestive cancer in Gaotai County from 2011 to 2015. Endoscopy with iodine staining and indicative biopsy was performed in the screening and the results were statistically analyzed.[Results] Among 5838 participants,140 cases(2.40%) of high grade intraepithelial neoplasia and cancer were detected;the detection rate of esophageal cancer,cardia cancer and gastric cancer was 0.98%(57 cases),0.57%(33 cases) and 0.86%(50 cases),respectively. The diagnosis rate of early cancers was 67.14%(94 cases). In 162 cases with precancerous lesions,105 were followed up(63.64%);and 6 new cancer cases were detected during follow-up,all of whom were early cases and received prompt treatment. [Conclusion] Endoscopy with iodine staining and indicative biopsy can effectively detect precancerous lesions and early cancer.
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