| 贾漫漫,陈元立,郑荣寿.家庭二手烟暴露与城市女性结直肠癌的相关研究[J].中国肿瘤,2017,26(5):355-360. |
| 家庭二手烟暴露与城市女性结直肠癌的相关研究 |
| Relationship Between Exposure to Secondhand Smoking at Home and Colorectal Cancer in Urban Chinese Women |
| 投稿时间：2017-02-08 |
| DOI：10.11735/j.issn.1004-0242.2017.05.A007 |
|
 |
| 中文关键词: 结直肠癌 流行病学 家庭二手烟 死亡率 |
| 英文关键词:colorectal cancer epidemiology secondhand smoking at home mortality |
| 基金项目:北京希望马拉松专项基金（2010YF48）；国家国际科技合作项目（2010DFB34180） |
|
| 摘要点击次数: 2154 |
| 全文下载次数: 658 |
| 中文摘要: |
| 摘 要：［目的］ 探讨家庭二手烟暴露与女性结直肠癌的关系。［方法］ 从1986～1988年我国吸烟与人口死因调查数据库选取23个城市为研究地区，30～79岁女性为研究对象，分析结直肠癌死者丈夫的吸烟史与结直肠癌死亡率的关系。［结果］ 研究对象结直肠癌死亡率为7.90/10万～26.39/10万，平均14.19/10万。相关分析发现，丈夫吸烟年限≥40年与女性结直肠癌死亡率呈正相关（r=0.48，P=0.02）。分层分析显示，丈夫吸烟指数≥20包年与30～39岁结直肠癌死亡率呈正相关（r=0.44，P=0.04）；丈夫日吸烟量10～19支、吸烟年限<30年与50～59岁结直肠癌死亡率相关系数分别为0.552、0.551，P<0.05；丈夫开始吸烟年龄<20岁、吸烟年限<30年、吸烟指数<10包年与70～79岁结直肠癌死亡率相关系数分别为0.51、0.46、0.60，P<0.05。［结论］ 家庭二手烟暴露可能是女性结直肠癌的重要危险因素。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the relationship between exposure to secondhand smoking at home and colorectal cancer in urban Chinese women.［Methods］ The relation between secondhand smoking at home and colorectal cancer mortality in 30～79 years old urban females was analyzed based on the national census data on causes of death and smoking from 1986 to 1988 in China.［Results］ Colorectal cancer mortality rate was 14.19/105 in 23 cities (range 7.90/105～26.39/105). The correlation analysis showed that husband smoking duration≥40 years was positively correlated with the mortality of colorectal cancer in females(r=0.48，P=0.02). Hierarchical analysis showed that the mortality was positively correlated with husband smoking≥20 pack-years in 30～39 age group(r=0.44，P=0.02) . In 50～59 age group，it was positively correlated with husband smoking cigarettes 10～19/day and smoking duration <30 years(r=0.552，0.551，P<0.05). In 70～79 age group，correlation coefficient of starting smoking age <20 years，smoking duration <30 years，smoking index <10 pack-years with mortality were 0.51，0.46，0.60，respectively (P<0.05). ［Conclusion］ Secondhand smoking at home is likely to be the important risk factor of colorectal cancer death in urban females in China. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |