| 宋国慧,李东方,孟凡书.中国食管癌高发区磁县同一区域10年后再次胃镜筛查结果分析[J].中国肿瘤,2017,26(3):175-180. |
| 中国食管癌高发区磁县同一区域10年后再次胃镜筛查结果分析 |
| Gastroscopic Results of Rescreening for Upper Digestive Tract Cancer in Cixian County of Hebei Province |
| 投稿时间：2016-01-04 |
| DOI：10.11735/j.issn.1004-0242.2017.03.A003 |
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| 中文关键词: 食管癌 贲门癌 远端胃癌 癌前病变 早诊早治 |
| 英文关键词:esophageal cancer carcinoma of gastric cardia cancer of distal stomach precancerous lesions early detection and treatment |
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| 中文摘要: |
| 摘 要：［目的］ 了解磁县上消化道癌第二轮早期筛查癌前状态及病变的检出率情况。［方法］ 收集2014年完成的40~69岁人群的上消化道癌内镜筛查资料，对符合对象按性别、年龄组统计食管、贲门、远端胃癌前状态及病变的检出率。［结果］ 纳入分析筛查对象2417例，食管活检率为26.85%，贲门活检率为12.37%，胃活检率为28.59%。食管癌及各级病变检出率分别为：鳞状上皮轻度异型增生检出率为3.52%，鳞状上皮中度异型增生检出率为0.91%，鳞状上皮重度异型增生检出率为0.70%，原位癌检出率为0.41%，黏膜内鳞状细胞癌检出率为0.17%，浸润性鳞癌检出率为0.04%，总体阳性检出率为1.32%。贲门癌及癌前病变检出率分别为：低级别上皮内肿瘤检出率为0.62%，高级别上皮内肿瘤检出率为0.17%，黏膜内腺癌检出率为0.29%，浸润性腺癌检出率为0.04%，总体阳性检出率为0.50%。远端胃癌及癌前病变检出率分别为：低级别上皮内肿瘤检出率为1.45%，高级别上皮内肿瘤检出率为0.04%，浸润性腺癌检出率为0.04%，总体阳性检出率为0.08%。［结论］ 2014年度总体检出率与10年前首次筛查资料相比明显有所下降，食管、贲门及远端胃的低级别上皮内肿瘤的检出率较低，与活检率及活检块数有一定的关系。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the gastroscopic results of rescreening for upper digestive tract cancer in Cixian county of Hebei province. ［Methods］ Screenings for upper digestive tract cancer among high risk residents aged 40~69 years old in two townships of Cixian county were conducted in 2004 and 2014，respectively. The results of second screening，including the detection rates of esophageal，cardia and distal gastric cancer by gender，age group were analyzed. ［Results］ A total of 2417 subjects were included in the analysis. The biopsy rates of esophagus，cardia and stomach were 26.85%，12.37% and 28.59%，respectively. For esophageal lesions，the detection rates of mild，moderate and severe dysplasia of squamous epithelium were 3.52%，0.91% and 0.70%，respectively；the detective rates of in situ carcinoma，squamous cell carcinoma and invasive squamous cell carcinoma were 0.41%，0.17% and 0.04%，respectively with an overall positive detection rate of 1.32%. For cardia lesions，the detection rates of low grade，high grade intraepithelial tumor and invasive adenocarcinoma were 0.62%，0.17% and 0.04% with an overall positive detection rate of 0.50%. For the distant gastric lesions，the detection rates of low grade，high grade intraepithelial tumor and invasive adenocarcinoma were 1.45%，0.04 and 0.04%，respectively with an overall positive detection rate of 0.08%. ［Conclusion］ The total detection rate is decreased significantly compared with the first screening 10 years before. The detection rate of low grade intraepithelial tumor of esophageal，cardia and distal gastric is low， which may be related to the biopsy rate and biopsy number. |
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