余长艳,周雪萌,赵 曙.老年套细胞淋巴瘤研究进展[J].中国肿瘤,2016,25(9):715-720.
老年套细胞淋巴瘤研究进展
Research Progress of Mantle Cell Lymphoma in the Elderly Patient
投稿时间:2015-12-28  
DOI:10.11735/j.issn.1004-0242.2016.09.A011
中文关键词:  套细胞淋巴瘤  化学免疫治疗  老年患者
英文关键词:mantle cell lymphoma  immuno-chemotherapy  elderly
基金项目:国家自然科学基金(81101703)
作者单位
余长艳 哈尔滨医科大学附属肿瘤医院 
周雪萌 哈尔滨医科大学附属肿瘤医院 
赵 曙 哈尔滨医科大学附属肿瘤医院 
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中文摘要:
      摘 要:套细胞淋巴瘤(mantle cell lymphoma,MCL)是一种独特的B细胞淋巴瘤,占非霍奇金淋巴瘤(non-Hodgkin’s lymphoma,NHL)的3%~10%,除自体干细胞移植(ASCT)外,MCL无其它可治愈的手段。MCL多见于老年男性,多数老年患者常合并基础疾病而不能耐受大剂量化疗和ASCT。全文主要分析MCL的病理生理、治疗、风险分层、预后以及老年患者的治疗选择。
英文摘要:
      Abstract:Mantle cell lymphoma (MCL) is a relatively rare B-cell lymphoma,accounted for about 3%~10% of all non-Hodgkin's lymphoma (NHL). There is no curative treatment,except allogeneic stem cell transplantation(ASCT) for patients with MCL. However,the majority patient of MCL is elderly men,and often accompanied with underlying diseases cannot tolerate high-dose chemotherapy and ASCT. The histological type,staging,risk stratification,prognosis and the treatment selection for elderly of MCL were analyzed in this article.
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