郭立文,郑家平,邵国良.原发性肝癌伴门静脉癌栓的治疗进展[J].中国肿瘤,2016,25(5):375-379.
原发性肝癌伴门静脉癌栓的治疗进展
Progress in Treatment of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
投稿时间:2015-12-23  
DOI:10.11735/j.issn.1004-0242.2016.05.A011
中文关键词:  原发性肝癌  门静脉  癌栓
英文关键词:hepatocellular carcinoma  portal vein  tumor thrombosis
基金项目:浙江省医药卫生一般资助项目(2013KYB041);浙江省医药卫生一般资助项目(2016KYA043);浙江省卫生高层次创新人才培养工程基金(2012-241)
作者单位
郭立文 浙江省肿瘤医院 
郑家平 浙江省肿瘤医院 
邵国良 浙江省肿瘤医院 
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中文摘要:
      摘 要:门静脉癌栓是原发性肝癌常见的表现之一,门静脉癌栓不仅导致肿瘤细胞在肝内播散和转移,且加重患者门静脉压力,常诱发上消化道大出血、肝功能衰竭等并发症,严重影响到肝癌患者的预后。近年来,虽然手术治疗、介入治疗、放疗、局部消融治疗、靶向治疗等在门静脉癌栓方面均有发展,但单模式治疗效果仍不理想,门静脉癌栓仍然是临床治疗的难点之一。全文就近些年来关于原发性肝癌伴门静脉癌栓的治疗新进展作一综述。
英文摘要:
      Abstract:Portal vein tumor thrombus is one of the common manifestations in patients with advanced hepatocellular carcinoma. The portal vein thrombi not only cause intrahepatic tumor cells dissemination and metastasis,but also induce massive bleeding of upper alimentary tract or failure of liver function. In recent years,with the development of surgical,interventional,radiotherapy,local ablation and target therapy,the outcome of hepatocellular carcinoma with portal vein thrombus significantly improved,but it’s still one of the difficulties in clinical treatment. In this paper,progress in the treatment of hepatocellular carcinoma with portal vein thrombus in recent years is summarized.
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