| 中文关键词: 小细胞肺癌 免疫治疗 临床试验 |
| 英文关键词:small cell lung cancer immunotherapy clinical trial |
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| 中文摘要: |
| 摘 要：肺癌是世界上常见的恶性肿瘤之一，其中小细胞肺癌约占14%。小细胞肺癌对一线化疗高度敏感，但多数患者在一线治疗缓解后很快出现复发或转移。随着分子生物学发展，免疫治疗可能突破小细胞肺癌治疗瓶颈，带来新希望。全文将对免疫节点抑制剂、抗独特型疫苗、细胞因子、过继性免疫治疗等治疗小细胞肺癌的临床研究作一综述。 |
| 英文摘要: |
| Abstract：Lung cancer is one of the common malignant tumors in the world，of which small cell lung cancer accounts for 14%. Small cell lung cancer is highly sensitive to first-line chemotherapy，but most of the patients relapse or transition after the first-line therapy quickly. With the development of molecular biology，immunotherapy may bring a breakthrough in the treatment of SCLC.This review focuses on immunotherapy of small cell lung cancer，such as immune-node inhibitors，specific vaccine，cytokines and curative effect of adoptive immunotherapy. |
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