| 廖雪芮,张修石,张红霞.MR弥散加权成像ADC值与直肠癌临床病理因素的相关性[J].中国肿瘤,2016,25(1):76-80. |
| MR弥散加权成像ADC值与直肠癌临床病理因素的相关性 |
| Correlation between ADC Value of MR Diffusion Weighted Imaging and Clinicopathological Factors in Rectal Cancer |
| 投稿时间：2015-05-15 |
| DOI：10.11735/j.issn.1004-0242.2016.01.A014 |
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| 中文关键词: 直肠癌 ADC值 临床病理因素 |
| 英文关键词:rectal cancer ADC value clinicopathological factors |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨直肠癌肿瘤的ADC值与直肠癌临床病理因素的相关性。［方法］ 选取2013年10月至2014年10月根治术的直肠癌初治患者360例，术前均行MRI平扫及DWI扫描，测量直肠癌肿瘤的ADC值。分析ADC值与各分组因素的相关性。［结果］ 单因素分析显示不同病理类型、不同分化程度的肿瘤ADC值差异均有统计学意义（P均<0.001），而不同大体分型、术后T分期、淋巴结转移及MRF浸润的肿瘤ADC值差异无统计学意义。多因素分析显示分化程度和T分期的交互作用对ADC值有显著性影响（P=0.045）。［结论］ 肿瘤ADC值与肿瘤的病理类型、分化程度及T分期的交互作用相关。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the correlation between ADC value and clinicopathological factors of rectal cancer. ［Methods］ A total of 360 patients with rectal cancer underwent radical surgery from October 2013 to October 2014 were enrolled，all of them underwent pelvic MRI and DWI scanning before surgery，measured the tumor ADC value of rectal cancer. The correlation between ADC value and clinicopathological factors was analyzed. ［Results］ Univariate analysis showed the tumor ADC value in various pathological types and in various degree of differentiations was all statistically significant(P all <0.001). The tumor ADC value between generally types，postoperative T stage，lymph node metastasis and MRF infiltration was all showed no significant difference. Multivariate analysis showed the interaction of differentiation and T stage had a significant impact on ADC value(P=0.045). ［Conclusion］ The tumor ADC value is associated with pathological type，tumor differentiation and the interaction of differentiation and T stage. |
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