陈文浩,杨 明,张艳桥.上皮—间质转化在恶性肿瘤中发生[J].中国肿瘤,2016,25(1):51-57. |
上皮—间质转化在恶性肿瘤中发生 |
Research Progress in Carcinogenesis Mechanism of Epithelial-Mesenchymal Transition in Cancer |
投稿时间:2015-04-07 |
DOI:10.11735/j.issn.1004-0242.2016.01.A010 |
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中文关键词: 上皮—间质转化 恶性肿瘤 机制 |
英文关键词:epithelial-mesenchymal transition cancer mechanism |
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中文摘要: |
摘 要:研究表明肿瘤细胞发生上皮—间质转化(EMT)时所涉及的分子机制相当复杂,涉及到的信号通路在转录、翻译和翻译后水平均发挥调控作用。全文就EMT在恶性肿瘤中发生机制的研究进展作一综述。 |
英文摘要: |
Abstract:Researches showed that there are complex molecular mechanism in epithelial-mesenchymal transition(EMT) of tumor cells. These signaling pathways involved in EMT play regulation roles in the transcriptional,translational and post-translational levels. The recent progress in carcinogenesis mechanism of EMT in cancer was discussed in this paper. |
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