王悠清,杜灵彬,李辉章.浙江省肿瘤登记地区2012年恶性肿瘤发病与死亡分析[J].中国肿瘤,2016,25(1):9-19.
浙江省肿瘤登记地区2012年恶性肿瘤发病与死亡分析
Analysis of Cancer Incidence and Mortality in Zhejiang Cancer Registries,2012
投稿时间:2015-11-30  
DOI:10.11735/j.issn.1004-0242.2016.01.A002
中文关键词:  肿瘤登记  恶性肿瘤  发病率  死亡率  浙江
英文关键词:cancer registration  malignant tumor  incidence  mortality  Zhejiang
基金项目:
作者单位
王悠清 浙江省癌症中心浙江省肿瘤防治办公室 
杜灵彬 浙江省癌症中心浙江省肿瘤防治办公室 
李辉章 浙江省癌症中心浙江省肿瘤防治办公室 
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中文摘要:
      摘 要:[目的] 描述和分析2012年浙江省肿瘤登记地区恶性肿瘤发病与死亡情况。[方法] 收集2012年浙江省8个肿瘤登记处上报的恶性肿瘤发病与死亡资料,按城乡、性别分层,分别计算恶性肿瘤发病与死亡粗率、标化率、累积率(0~74岁)、截缩率、年龄别率、地区别率以及前10位恶性肿瘤发病与死亡顺位和构成等。并采用2000年中国标准人口年龄构成和Segi’s世界标准人口年龄构成计算年龄标准化率。[结果] 2012年浙江省8个肿瘤登记地区覆盖人口11 127 744人,约占浙江省户籍人口的20.34%。共报告恶性肿瘤新发病例35 771例,死亡病例20 560例。病理学诊断比例(MV%)为74.86%,只有死亡医学证明书比例(DCO%)为1.58%,死亡发病比(M/I)为0.57。浙江省恶性肿瘤粗发病率为321.46/10万,中标率为200.91/10万,世标率为193.01/10万,男性发病率高于女性,城市地区发病率高于农村地区。癌症发病在40岁以后快速上升,在80~84岁年龄组达到高峰。发病前10位恶性肿瘤依次为肺癌、结直肠癌、胃癌、甲状腺癌、肝癌、乳腺癌、食管癌、宫颈癌、胰腺癌和脑肿瘤。浙江省恶性肿瘤粗死亡率为184.76/10万,中标率为102.36/10万,世标率为101.03/10万,男性死亡率高于女性,农村地区死亡率高于城市地区。癌症死亡在45岁以后快速上升,在80~84岁年龄组达到高峰。死亡前10位恶性肿瘤依次为肺癌、肝癌、胃癌、结直肠癌、食管癌、胰腺癌、淋巴瘤、白血病、脑肿瘤和胆囊癌。[结论] 肺癌、消化系统恶性肿瘤和女性乳腺癌是威胁浙江省居民健康的主要癌种,这些肿瘤仍是浙江省肿瘤防治工作的重点。同时,甲状腺癌发病增长速度较快,是肿瘤防治面临的新挑战。
英文摘要:
      Abstract:[Purpose] To investigate the cancer incidence and mortality in Zhejiang cancer registries in 2012. [Methods] The data were collected from 8 population-based cancer registries of Zhejiang province. Cancer incidence and mortality stratified by gender and regions were analyzed. Crude rate,age-standardized rate,age-specific and region-specific rate,cumulative rate and truncated rate were calculated. The proportion of 10 common cancers in different groups were also calculated. Chinese population census in 2000 and Segi’s population were used for calculating age-standardized incidence and mortality. [Results] The 8 cancer registries covered a total of 11 127 744 population,accounting for 20.34% of Zhejiang population. The total reported new cancer cases and deaths were 35 771 and 20 560,respectively. The morphology verified cases (MV%) accounted for 74.86%,and 1.58% of cases were identified through death certifications only (DCO%) with mortality to incidence ratio(M/I ratio) of 0.57. The crude incidence in Zhejiang cancer registration areas was 321.46/105;the age-standardized incidence by Chinese standard population and by world standard population were 200.91/105 and 193.01/105,respectively. The incidence in male was higher than that in female,and the incidence in urban areas was higher than that in rural areas. Cancer incidence increased rapidly after the age of 40 years and reached the peak at the age group of 80~84 years. The top 10 incidence of cancers were lung cancer,colorectum cancer,stomach cancer,thyroid cancer,liver cancer,breast cancer,esophagus cancer,cervix cancer,pancreas cancer and brain tumor. The crude mortality in Zhejiang cancer registration areas was 184.76/105;the age-standardized mortality rates by Chinese standard population and by world standard population were 200.91/105 and 193.01/105,respectively. The mortality in male was higher than that in female,and the male in rural areas was higher than that in urban areas. Cancer mortality increased rapidly after the age of 45 years and reached the peak at the age group of 80~84 years. The top 10 mortality of cancers were lung cancer,liver cancer,stomach cancer,colorectum cancer,esophagus cancer,pancreas cancer,lymphoma,leukemia,brain tumor and gallbladder cancer. [Conclusions] Lung cancer,digestive system malignancies and breast cancer are the most common cancers in Zhejiang province. These cancers should be focused on. The incidences of thyroid cancer and cervical cancer increased rapidly. Prevention and control measures should be implemented on these cancers.
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