| 朱美英,张桃莉,吴巧敏.既往血吸虫病感染人群大肠癌发病风险研究[J].中国肿瘤,2015,24(11):900-904. |
| 既往血吸虫病感染人群大肠癌发病风险研究 |
| Study on the Risk of Colorectal Cancer in the Population with Past Schistosomiasis Infection |
| 投稿时间：2015-02-13 |
| DOI：10.11735/j.issn.1004-0242.2015.11.A003 |
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| 中文关键词: 既往血吸虫病感染 大肠癌 危险因素 |
| 英文关键词:past Schistosomiasis infection colorectal cancer risk factors |
| 基金项目:上海市松江区医学合作课题（2011LX-12） |
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| 摘要点击次数: 1947 |
| 全文下载次数: 978 |
| 中文摘要: |
| 摘 要：［目的］ 分析既往血吸虫病疫区感染人群大肠癌发病风险，为制定大肠癌预防和控制策略提供依据。［方法］ 比较上海市松江区既往血吸虫病疫区与非疫区大肠癌发病情况；并对2012年220 175名筛查对象的筛查资料进行非条件Logistic回归分析。［结果］ 2002~2009年松江区大肠癌发病呈上升趋势；松江区既往血吸虫病疫区(车墩、洞泾、中山、佘山、泗泾、九亭、新桥)的大肠癌发病率高于其他非疫区（岳阳、泖港、小昆山、叶榭、方松、石湖荡、新浜、永丰）；2005~2009年松江区大肠癌发病率高于与上海市其他非血吸虫病疫区区县。非条件性Logistic回归分析表明血吸虫感染与大肠癌发病相关（OR=6.048，95%CI：5.249~6.971，P<0.001）。［结论］ 既往血吸虫病疫区感染人群大肠癌发病风险增高。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the risk of colorectal cancer in the population with past Schistosomiasis infection，and to provide evidences for the prevention and treatment of colorectal cancer. ［Methods］ The standardized incidence of colorectal cancer between the past Schistosomiasis epidemic and un-epidemic areas in Songjiang district，Shanghai compared and analyzed，and the data of 220 175 screening objects in 2012 was analyzed by Logistic regression. ［Results］ The incidence of colorectal cancer was increasing from 2002 to 2009 in Songjiang district. The incidence of colorectal cancer in past Schistosomiasis epidemic areas (Chedun，Dongjing，Zhongshan，Sheshan，Sijing，Jiuting，Xinqiao was higher than that in un-epidemic areas (Yueyang，Maogang，Xiaokunshan，Yexie，Fangsong，Shihudang，Xinbang，Yongfeng in Songjiang district. The incidence of colorectal cancer in Songjiang district was higher than that in past Schistosomiasis un-epidemic districts of Shanghai. The Logistic regression showed that the occurrence of colorectal cancer was related to the Schistosomiasis infection (OR=6.048，95%CI：5.249~6.971，P<0.001). ［Conclusion］ The risk of colorectal cancer increased in the population with past Schistosomiasis infection. |
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