赵 健,赵宇倩,王婷婷.R-way阴道镜智能诊断评估技术识别宫颈高级别病变的能力[J].中国肿瘤,2015,24(10):884-888.
R-way阴道镜智能诊断评估技术识别宫颈高级别病变的能力
The Capability of R-way Intelligent Colposcopy Evaluation System to Detect High-grade Squamous Intraepithelial Lesion of the Cervix
投稿时间:2014-12-09  
DOI:10.11735/j.issn.1004-0242.2015.10.A018
中文关键词:  R-way阴道镜智能诊断评估  宫颈高级别病变  宫颈癌筛查  阴道镜
英文关键词:R-way intelligent colposcopy evaluation system  high-grade squamous intraepithelial lesion  cervical cancer screening  colposcopy
基金项目:
作者单位
赵 健 北京大学第一医院 
赵宇倩 北京协和医学院中国医学科学院肿瘤医院 
王婷婷 中国疾病预防控制中心 
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中文摘要:
      摘 要:[目的] 探讨R-way阴道镜智能诊断系统识别宫颈高级别病变的能力。[方法] 选取498例经阴道镜检查组织病理诊断HSIL+ (包括CIN2、CIN3、原位腺癌、浸润癌)的病例,分析阴道镜不同时间、不同检查下的颜色变化,通过“红厚白”、“红白A”、“红白黄”以及阴道镜观察到出血(溃疡)、细胞学异常ASC-H、HSIL、SCC、AGC+(包括AGC-NOS、AGC-FN)、AIS、Adca作为R-way系统评估方法拟诊宫颈高级别病变的指标。[结果] R-way系统的5项指标联合评估宫颈高级别病变的灵敏度为94.78%。最常见的异常指标为“红厚白”、“红白A”、“红白黄”以及细胞学异常ASC-H、HSIL、SCC及AGC+。[结论] R-way诊断系统不同评估指标相结合,可正确识别宫颈高级别病变,但临床应用尚需大样本数据验证其特异度等指标。
英文摘要:
      Abstract:[Purpose] To explore the capability of R-way intelligent colposcopy evaluation system to detect high-grade squamous intraepithelial lesion of the cervix. [Methods] The 498 cases of histopathology confirmed HSIL+(CIN2,CIN3,carcinoma in situ,invasive cancer) were selected to observed the changes along with the time and staining. The “red think white”,“red white A (atypical vessels)”,“red white yellow”,bleeding observed under colposcopy and abnormal cytology (ASC-H,HSIL,SCC,AGC including AGC-NOS,AGC-FN,AIS,Adca) were selected as the indicators of R-way evaluation system to detect HSIL+. [Results] The accumulation detection rate of the five indicators was 94.78%. The “red think white”,“red white A (atypical vessels)”,“red white yellow” and cytology as ASC-H,HSIL,SCC and AGC+ were the most frequently found abnormal indicators.[Conclusions] The combination of different indicators of R-way diagnostic system could correctly detect HSIL+ cases. It is promising but larger sample size study is needed to evaluate the specificity and other validation indicators.
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