| 蔡玉群,李 薇,万惠卿.杭州市拱墅区已婚妇女宫颈液基细胞学筛查结果分析[J].中国肿瘤,2015,24(5):390-393. |
| 杭州市拱墅区已婚妇女宫颈液基细胞学筛查结果分析 |
| An Analysis of Cervical Liquid-based Cytology Testing Results of Married Women in Gongshu District，Hangzhou City |
| 投稿时间：2014-10-30 |
| DOI：10.11735/j.issn.1004-0242.2015.05.A009 |
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| 中文关键词: 宫颈癌 宫颈液基细胞学 筛查 杭州市 |
| 英文关键词:cervical cancer liquid-based cytology testing screening Hangzhou |
| 基金项目:浙江省人口计生委科研项目（编号JSW2013-B003） |
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| 中文摘要: |
| 摘 要：［目的］ 分析杭州市拱墅区女性宫颈病变情况，为宫颈癌防治提供参考依据。［方法］ 2013年采取整群抽样方法对杭州市拱墅区女性11 276名居民入组研究，研究对象行妇科检查，收集脱落细胞标本，标本采用Cellslide膜式液基细胞学检测和TBS分级诊断系统。［结果］ 2013年液基细胞学检查11 276人，标本满意率达99.05%。液基细胞学检查异常病变包括不能明确意义不典型鳞状细胞(atypical squamous cells of unknown significance，ASCUS)、不除外高度鳞状上皮内病变的不典型鳞状上皮细胞(atypical squamous cells，cannot exclude HSIL，ASC-H)、低度鳞状上皮内病变(low grade squamous intraepithelial lesions，LSIL)、高度鳞状上皮内病变(high grade squamous intraepithelial lesions，HSIL) 不典型腺细胞(atypical glandular cells，AGC)共425人，占3.8%。不同年龄组宫颈液基细胞学异常比例差异有统计学意义（χ2=313.036，P=0.000）。宫颈细胞学异常高发人群集中在30～55岁，其中88.40%的ASCUS+ASC-H发生在30～55岁；91.10%的LSIL发生在26～55岁，HSIL全部病例均集中在30～60岁。［结论］ 宫颈细胞学异常高发人群集中在30～55岁，30～55岁的妇女务必常规进行细胞学检查。宫颈液基细胞学检查发现大量癌前病变患者，为制定妇女卫生保健政策提供了科学依据。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the status of cervical lesions in married women in Gongshu district，Hangzhou city，and to provide a scientific basis for prevention of cervical cancer. ［Methods］ A total of 11276 women were enrolled into this study by stratified cluster sampling method in Gongshu district，Hangzhou in 2013. Cellslide liquid-based cytology testing(LCT) for cervical cancer screening in the women was carried out，and the TBS diagnosis system were used. ［Results］ Of 11276 women received LCT，the satisfaction rate of sample was 99.05%. Four hundred and twenty-five women were found abnormal lesions including atypical squamous cells of unknown significance (ASCUS)，atypical squamous cells，cannot exclude HSIL(ASC-H)，low grade squamous intraepithelial lesions(LSIL)，high grade squamous intraepithelial lesions(HSIL) and atypical glandular cells (AGC). The abnormal lesions accounted for 3.8% of all tested women. Proportion of abnormal cervical liquid-based cytology was significantly different in different age groups (χ2=313.036，P=0.000). Cervical abnormal lesions was concentrated in 30 to 55 years old women，88.40% of ASCUS / ASC-H occurred in 30 to 55 years old；91.10% of LSIL occurred in 26 to 55 years old； all HSIL occurred in 30~60 years old. ［Conclusion］ Routine cytology examination must be carried out in 30 to 55 years old women. Effectiveness of cervical liquid-based cytology testing can detect a large number of precancerous lesions，and provide a scientific basis for women’s health care. |
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