| 朱云峰,朱胜强,沈永洲.不同变量问卷表在结直肠癌早诊早治筛查中的效果评价[J].中国肿瘤,2015,24(5):380-384. |
| 不同变量问卷表在结直肠癌早诊早治筛查中的效果评价 |
| The Effect of Variables Questionnaire in Screening for Colorectal Cancer Early Diagnosis and Treatment |
| 投稿时间：2014-11-13 |
| DOI：10.11735/j.issn.1004-0242.2015.05.A007 |
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| 中文关键词: 结直肠癌 筛查 病史 问卷调查 灵敏度 特异性 |
| 英文关键词:colorectal cancer screening history questionnaire sensitivity specificity |
| 基金项目:浙江省公益性技术应用项目研究（2013C33127） |
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| 摘要点击次数: 1971 |
| 全文下载次数: 965 |
| 中文摘要: |
| 摘 要：［目的］ 评价两种不同变量问卷调查表在结直肠癌筛查中的效果，为进一步优化筛查方案提供科学依据。［方法］ 根据《中国癌症筛查及早诊早治指南》制订结直肠癌筛查实施方案，对海宁市40~74岁目标人群开展筛查。初筛包括流行病学问卷调查和大便隐血试验（FOBT）确定高危人群，其中部分应检对象采用新版问卷调查表，即在原病史问卷内容的基础上增加了腹痛、贫血、大便习惯性质改变和不明原因体重减轻4个变量。精筛即对高危人群进一步做电子结肠镜检查。［结果］ 海宁市2010~2012年完成流行病学问卷调查240 177人，顺应率88.25%。采用新版病史问卷调查91 997人，病史阳性率为6.99%；检出肠道病变（息肉、腺瘤、癌）2369例。病史阳性诊断肠道病变的灵敏度为47.24%，特异性为71.71%。旧版病史问卷调查148 180例，病史阳性率为5.54%，检出肠道病变4183例，病史阳性诊断肠道病变的灵敏度为38.90%，特异性为69.37%。［结论］ 新版问卷调查表病史阳性率高、对肠道病变灵敏度、特异性均高于旧版，在进行结直肠癌筛查时新版问卷调查表值得推荐。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the effect of new and old version of history questionnaire for colorectal cancer screening，and to provide the scientific basis for the further optimization of the screening program.［Methods］ Based on the China Cancer Screening and Early Diagnosis and Early Treatment for Colorectal Cancer Screening Guidelines，target population with 40~74 years-old in Haining city were carried out screening，including epidemiological survey and fecal occult blood test(FOBT) to identify high-risk populations. New questionnaire increased 4 variables including abdominal pain，anemia，defecated changes，unexplained weight loss. Fine screen for high-risk groups underwent further electronic colonoscopy.［Results］ A total of 240 177 people completed the epidemiological survey with rate of 88.25% in Haining city from 2010 to 2012. Of 91 997 people with new version questionnaire，the positive medical history was 6.99%；and 2369 people were checked out the intestinal lesions (polyp，adenoma，carcinoma). The medical history diagnosed intestinal lesions with a sensitivity of 47.24% and a specificity of 71.71%. Of 148 180 people with old version questionnaire，the positive medical history was 5.54%，and 4183 people were checked out the intestinal lesions. The medical history diagnosed intestinal lesions with a sensitivity of 38.90% and a specificity of 69.37%. ［Conclusion］ The new version questionnaire has a higher detected rate of medical history，and a higher sensitivity and specificity than the old version questionnaire for diagnosing intestinal lesions. The new version of the questionnaire is recommended for screening for colorectal cancer. |
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