| 宋国慧,孟凡书,白文龙.磁县食管癌高发区贲门癌及其癌前病变检出率分析[J].中国肿瘤,2015,24(2):110-113. |
| 磁县食管癌高发区贲门癌及其癌前病变检出率分析 |
| An Analysis of Gastric Cardia Adenocarcinoma and Its Precancerous Lesions in High Incidence Area of Esophageal Cancer in Ci County |
| 投稿时间：2014-06-09 |
| DOI：10.11735/j.issn.1004-0242.2015.02.A007 |
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| 中文关键词: 贲门癌 癌前病变 高危人群 早诊早治 |
| 英文关键词:gastric cardia adenocarcinoma precancerous lesions high risk population early detection and treatment |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨磁县食管癌高发区居民贲门癌及其癌前病变的分布情况。［方法］ 回顾整理磁县2005~2009年40~69岁高危人群的内镜筛查资料，按性别，年龄统计贲门癌及其癌前病变的检出率。［结果］ 纳入分析普查对象11 423人，贲门活检率95.71%。贲门低级别上皮内肿瘤检出率为2.07%，高级别上皮内肿瘤为0.30%，黏膜内腺癌为0.23%、浸润性腺癌为0.18%。各级别病变检出率男性均高于女性，并且随年龄的增高病变检出率增加。［结论］ 磁县食管癌高发区40~69岁人群存在无症状贲门癌及其癌前病变的患者，年龄和性别与检出率关系密切。食管癌高发区上消化道癌筛查应重视贲门部位的检查。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the distribution of gastric cardia adenocarcinoma and its precancerous lesions in high incidence area of esophageal cancer in Ci County. ［Method］ The data from the endoscopic screening project in Ci County from 2005 to 2009 were analyzed retrospectively，and the detection rate based on gender and age were calculated. ［Results］ Among 11 423 participants，95.71% had biopsies from the gastric cardia. The detection rate was 2.07% for Low-grade intraepithelial neoplasia，0.30% for high-grade intraepithelial neoplasia，0.23% for intramucosal adenocarcinoma，and 0.18% for invasive adenocarcinoma. The detection rate for each grade lesion in male was higher than that in female and the detection rate increased along with age. ［Conclusions］ There are no symptoms of cardiac carcinoma and its precancerous lesions of patients aged 40～69 in high incidence areas of esophageal cancer in Cixian，age and gender are closely related to detection rate. Upper gastrointestinal screening should pay attention to the cardia esophageal cancer examination in high incidence area. |
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