| 孙元珏,祁伟祥,姚 阳.还原型谷胱甘肽与肿瘤化疗相关性肝损伤的防治[J].中国肿瘤,2015,24(1):57-63. |
| 还原型谷胱甘肽与肿瘤化疗相关性肝损伤的防治 |
| Prevention and Treatment of Glutathione in Chemotherapy-induced Liver Injury |
| 投稿时间：2014-03-31 |
| DOI：10.11735/j.issn.1004-0242.2015.01.A013 |
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| 中文关键词: 谷胱甘肽 肿瘤 化疗 肝损伤 |
| 英文关键词:glutathione tumor chemotherapy liver injury |
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| 中文摘要: |
| 摘 要：随着恶性肿瘤发病率逐年上升，化疗相关性肝损伤发病率也日益增加。还原型谷胱甘肽作为常用的护肝药物，可与化疗药物及其代谢产物结合形成低毒性产物，保护或恢复肝细胞功能。全文对还原型谷胱甘肽在肿瘤化疗相关性肝损伤中的机制及防治作一综述。 |
| 英文摘要: |
| Abstract：As cancer incidence increased year by year，chemotherapy-induced liver injury incidence is increasing. As a common liver drug，glutathione can be combined with chemotherapy drugs and their metabolites into low toxicity products，in order to protect or restore liver cell function. This article reviews the mechanism of restored glutathione for prevention of cancer chemotherapy-induced liver injury. |
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