| 丛明华,程国威,李淑娈.管饲营养支持对于食管癌放化疗患者作用的研究[J].中国肿瘤,2014,23(12):1028-1033. |
| 管饲营养支持对于食管癌放化疗患者作用的研究 |
| The Effect of Tube Feeding on Esophageal Cancer Patients with Concurrent Chemo-radiotherapy |
| 投稿时间：2014-05-15 |
| DOI：10.11735/j.issn.1004-0242.2014.12.A015 |
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| 中文关键词: 食管癌 同步放化疗 管饲 口服营养素补充 预后 并发症 |
| 英文关键词:esophageal cancer chemo-radiotherapy tube feeding oral nutritional supplements |
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| 中文摘要: |
| 摘 要：［目的］ 探讨管饲营养支持对食管癌同步放化疗患者的作用。 ［方法］食管癌拟行放化疗患者40例，随机分为管饲营养支持组（TF组）20例，口服营养素补充组（ONS组）20例，观察放疗结束时患者营养状况、并发症发生率、按治疗计划完成率、住院时间及费用。［结果］ TF组患者放疗结束时各项营养及血液指标均优于ONS组（P＜0.05），骨髓抑制发生率低于ONS组(25% vs 60%，P＜0.05)。TF组患者均按计划完成治疗，ONS组4例因严重并发症中断或延迟治疗（P＜0.05），TF组住院时间平均缩短3.3d（P＜0.05），住院费用减少11100元/人次（P＜0.05）。［结论］ 对于食管癌放疗患者，管饲营养支持更能够使患者达到喂养目标，维持良好的营养状况，降低并发症发生率，提高治疗耐受性，缩短住院时间，降低住院费用。 |
| 英文摘要: |
| Abstracts：［Purpose］ To investigate the effect of tube feeding on esophageal cancer patients with concurrent chemo-radiotherapy. ［Methods］ Forty cases with esophageal cancer patients with concurrent chemo-radiotherapy were randomly divided into tube feeding (TF) group (n=20) and oral nutritional supplements (ONS) group (n=20). At the end of chemo-radiotherapy，nutritional status，incidence of complications，and completion rates of radiotherapy were evaluated. Besides，length of hospital stay (LOS) and cost were also compared between the two groups. ［Results］ Compared to ONS group，nutrition and blood parameter values in TF group were better (P＜0.05)，and the myelosuppression rate was lower (25% vs 60%，P＜0.05). In addition，the patients in TF group all completed the treatment plan while 4 patients in ONS group were interrupted or delayed(P＜0.05). At last，the average LOS decreased by 3.3 days (P＜0.05) and hospitalization cost reduced 11100 RMB person-times(P＜0.05) for TF group patients. ［Conclusion］ Tube feeding can help obtain feeding target，maintain nutritional status and improve treatment compliance and tolerance of esophageal carcinoma patients with concurrent chemo-radiotherapy and help to shorten LOS and reduce cost. |
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