房 莉,章诗伟,李 晶.脑胶质瘤患者预后影响因素分析[J].中国肿瘤,2014,23(12):1019-1023.
脑胶质瘤患者预后影响因素分析
An Analysis on Prognostic Factors in Patients with Glioma
投稿时间:2014-05-20  
DOI:10.11735/j.issn.1004-0242.2014.12.A013
中文关键词:  胶质瘤  预后  生存率
英文关键词:glioma  prognosis  survival
基金项目:
作者单位
房 莉 广州军区武汉总医院 
章诗伟 广州军区武汉总医院 
李 晶 广州军区武汉总医院 
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中文摘要:
      摘 要:[目的] 探讨脑胶质瘤患者预后影响因素,以提高胶质瘤患者术后生存率。[方法] 外科手术后经病理确诊为脑胶质瘤的患者158例,查找病历和电话随访收集其资料,生存分析单因素分析使用Kaplan-Meier法计算生存率,并采用Log-rank检验;多因素分析采用Cox分析。[结果] 单因素分析表明影响预后的因素有:年龄、肿瘤级别、KPS评分、术后放疗和化疗。多因素分析显示年龄、肿瘤级别、KPS评分、术后放疗和化疗是影响预后的独立因素。[结论] 年龄小、级别低、KPS评分高的患者术后预后较好,术后辅助放疗或者化疗有助于改善预后。
英文摘要:
      Abstract:[Purpose] To investigate the prognostic factors and to improve the survival in patients with glioma after operation. [Methods] A total of 158 patients with gliomas confirmed by pathology were collected. The clinical data was collected by scanning medical records and telephone follow-up.Kaplan-Meier method and Log-rank test was used in univariate analysis whereas Cox analysis was used in multivariate analysis.[Results] Univariate analysis and multivariate analysis both showed that the prognostic factors were age,pathology grade,KPS score,postoperative radiotherapy and chemotherapy.[Conclusions] Better prognosis of glioma patients are depending on lower age and pathology grade,higher KPS score,and postoperative radiotherapy and chemotherapy.
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