| 李宝重,刘世伟,何 明.食管胃结合部腺癌术后早期复发与死亡的相关危险因素[J].中国肿瘤,2014,23(7):608-611. |
| 食管胃结合部腺癌术后早期复发与死亡的相关危险因素 |
| Relative Risk Factors of Early Recurrence and Death in Patients with Adenocarcinoma of Esophagogastric Junction Postoperation |
| 投稿时间：2013-11-20 |
| DOI：10.11735/j.issn.1004-0242.2014.07.A015 |
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| 中文关键词: 食管胃结合部腺癌 外科治疗 预后 生存分析 |
| 英文关键词:adenocarcinoma of esophagogastric junction surgery prognosis survival analysis |
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| 中文摘要: |
| 摘 要：［目的］ 探讨食管胃结合部腺癌患者术后1年内复发与死亡的相关危险因素。［方法］ 回顾性分析了2006年3月至2007年2月在河北医科大学第四医院胸外科诊治的387例食管胃结合部腺癌患者的临床病例资料。［结果］ 全组患者1年生存率为79.0%，5年生存率为28.7%，术后1年内复发死亡的患者71例，术后5年以上未复发的患者为109例。单因素分析显示：性别、肿瘤最大直径、肿瘤浸润深度、淋巴结转移及残端是否阳性是影响预后的因素。多因素分析显示：性别（P=0.037）、肿瘤最大直径（P=0.030）、淋巴结转移（P=0.000）是影响预后的独立危险因素。［结论］ 食管胃结合部腺癌的预后仍较差，复发转移依然是主要的致死原因。而性别、肿瘤最大直径和淋巴结转移是预测术后早期复发转移的独立危险因素。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the relative risk factors of early recurrence and death within 1 year after surgery in patients with adenocarcinoma of esophagogastric junction(AEG). ［Methods］ The records of 387 patients with AEG who underwent surgery in the Fourth Hospital of Hebei Medical Universiy from March 2006 to February 2007 were reviewed. ［Results］ The overall 1-year and 5-year survival rates were 79.0% and 28.7%，respectively. Seventy-one patients died within 1 year and 109 patients survived more than 5 years without recurrence. Univariate analysis showed that gender，maximum tumor diameter，tumor invasion depth，metastatic lymph nodes and margin status were the prognostic risk factors of AEG. Multivariate analysis demonstrated that gender，maximum tumor diameter and metastatic lymph node were independent prognostic factors. ［Conclusions］ The prognosis of AEG patients remains poor，and recurrence is shown to be as the main cause of death. Gender，maximum tumor diameter and metastatic lymph nodes are independent prognostic factors predicting early recurrence and death in patients with AEG. |
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