| 陈万源,范永田,刘 勇.浙江省肿瘤医院近20年结直肠癌[J].中国肿瘤,2014,23(7):563-566. |
| 浙江省肿瘤医院近20年结直肠癌 |
| An Analysis of Clinical Characteristics of Colorectal Cancer in Recent Past 20 Years in Zhejiang Cancer Hospital |
| 投稿时间：2014-01-27 |
| DOI：10.11735/j.issn.1004-0242.2014.07.A007 |
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| 中文关键词: 结直肠癌 临床特征 浙江省肿瘤医院 |
| 英文关键词:colorectal cancer clinical characteristics Zhejiang Cancer Hospital |
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| 中文摘要: |
| 摘 要：［目的］ 了解浙江省肿瘤医院近20年结直肠癌临床特征变化情况。［方法］ 收集近20年三个不同时间段在浙江省肿瘤医院住院治疗的结直肠癌病例，分别为1988年1月至1991年12月（A组），1998年1月至2001年4月（Ｂ组）和2012年1月至2013年1月（Ｃ组），三组结直肠癌临床特征进行比较分析。［结果］ 近20年结直肠癌的男女比例逐渐增高，直肠癌发病比例明显下降，从78.1%下降至57.7%；发病年龄逐渐后延，平均年龄从49.5岁上升至58.1岁。组织学分型中分化、高分化腺癌比例较高，A、B和C组中分别为54.8%、54.7%和61.1%，DukesA~B期比例均高于DukesC~D期，其中DukesD期比例明显下降。［结论］ 浙江省肿瘤医院近20年收治的结直肠癌患者平均年龄逐渐增高，直肠癌比例明显下降，同时，DukesD期比例明显下降。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the clinical characteristics of colorectal cancer in recent 20 years in Zhejiang Cancer Hospital. ［Methods］ The clinical data of inpatients with colorectal cancers of Zhejiang Cancer Hospital in 3 periods as following 1988.1~1991.12(Group A)，1998.1~2001.4(Group B) and 2012.1~2013.1(Group C) were analyzed. The clinical characteristics of colorectal cancer were analyzed. ［Results］ Recent 20 years，the male to female ratio of colorectal cancer was gradually increased，the proportion of rectal cancer was significantly decreased from 78.1% to 57.7%. The average age of patient was gradually delayed from 49.5 years to 58.1 years. The proportion of moderately and well differentiated cancers accounted for 54.8%，54.7% and 61.1% in group A，B and C respectively，which was higher than that of poorly differentiated cancer. The proportion of Dukes A~B stage was higher than that in Dukes C~D stage in the 3 groups，and the proportion of Dukes D stage was significantly decreased in the past 20 years.［Conclusion］ The average age of patients with colorectal cancer gradually increase and the proportion of rectal cancer and Dukes D stage significantly decrease in recent 20 years in Zhejiang Cancer Hospital . |
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