| 张隽瑜,李琳洁.骨髓增生异常综合征DNA甲基化及其治疗机制的进展[J].中国肿瘤,2014,23(6):497-501. |
| 骨髓增生异常综合征DNA甲基化及其治疗机制的进展 |
| Progress in DNA Methylation in Patients with Myelodysplastic Syndrome and Its Therapeutic Mechanism |
| 投稿时间：2013-07-23 |
| DOI：10.11735/j.issn.1004-0242.2014.06.A012 |
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| 中文关键词: DNA甲基化：骨髓增生异常综合征：去甲基化药物 |
| 英文关键词:DNA methylation： myelodysplastic syndrome： myelodysplastic syndrome |
| 基金项目: |
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| 摘要点击次数: 1758 |
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| 中文摘要: |
| 摘 要：骨髓增生异常综合征(myelodysp lastic syndrome，MDS)仍为血液病学较难攻克的一大主题，近年由于DNA甲基化研究的进展及DNA去甲基化药物的开发、使用，为MDS的治疗提供了更多可能的靶点。全文就近年DNA甲基化及去甲基化治疗相关机制的研究进展作一介绍。 |
| 英文摘要: |
| Abstract：Myelodysplastic syndrome (MDS) is a haematoloic disease which is still difficult to conquer. In recent years，due to the progress of DNA methylation，and development and application of demethylation agents，these provide more potential targets for the treatment of MDS. The progress of DNA methylation and demethylation therapy and its related mechanism were present in this article. |
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