| 薛学锋,尹燕慈,张启南.原发性肝癌患者与其一级亲属的血糖水平分析[J].中国肿瘤,2014,23(4):289-291. |
| 原发性肝癌患者与其一级亲属的血糖水平分析 |
| An Analysis of Blood Glucose Level in Patients with Liver Cancer and in Their First Degree Relatives |
| 投稿时间：2013-09-24 |
| DOI：10.11735/j.issn.1004-0242.2014.04.A004 |
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| 中文关键词: 肝癌 血糖 HbsAg 一级亲属 |
| 英文关键词:liver cancer diabetes mellitus blood glucose HBsAg,relatives |
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| 中文摘要: |
| 摘 要：［目的］ 分析启东地区原发性肝癌患者与其一级亲属及对照者血糖水平。 ［方法］肝癌患者448例（肝癌组）、肝癌患者一级亲属1282例（亲属组）及健康体检人员1236例（对照组），均作HBsAg、空腹血糖检测，以χ2检验进行统计学处理。［结果］ 肝癌组的高血糖检出率显著性高于亲属组和对照组（χ2=16.64、64.80，P均<0.01）；亲属组显著性高于对照组（χ2=24.33，P<0.01）。肝癌组HBsAg阳性检出率显著性高于亲属组和对照组（χ2=382.91、726.61，P均<0.01）；亲属组显著性高于对照组（χ2=91.04，P<0.01）。［结论］ 高血糖和HBsAg可能是原发性肝癌的独立或协同危险因素，肝癌患者的一级亲属也可能是原发性肝癌的易感人群，应予高度重视。 |
| 英文摘要: |
| Abstract：［Purpose］ To analysis the blood glucose level in patients with liver cancer and in their first degree relatives. ［Method］ Four hundred and forty-eight cases with liver cancer，1282 cases of their first degree relatives，and 1236 healthy person as control were enrolled. The HBsAg and fasting blood glucose were detected. Chi-square test was used for statistic analysis. ［Results］The hyperglycemia rate in liver cancer group was significant higher than that in relatives group and control group(χ2=16.64，64.80，respectively，P all<0.01)，and hyperglycemia rate in relatives group was higher than that in control group(χ2=24.33，P<0.01). The positive rate of HBsAg in liver cancer group was significant higher than that in relatives group and control group(χ2=382.91 and 726.61，respectively，P all<0.01)，and the positive rate in relatives group was higher than that in control group (χ2=91.04，P<0.01). ［Conclusion］ High blood glucose level and HBsAg positivity may be independent or synergic risk factors for liver cancer. Perhaps the relatives of these patients are a group of people susceptible to liver cancer.Control and prevention should be enhanced. |
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