宫霄欢,余金明,王继伟.社会心理干预影响乳腺癌患者生命质量的效果评价[J].中国肿瘤,2014,23(4):275-280.
社会心理干预影响乳腺癌患者生命质量的效果评价
Trend Analysis of Incidence of Esophageal Cancer in 1999~2011 in Taixing City,Jiangsu Province
投稿时间:2013-07-16  
DOI:10.11735/j.issn.1004-0242.2014.04.A002
中文关键词:  乳腺癌  社会心理干预  生命质量  Meta分析
英文关键词:breast cancer  psychosocial intervention  quality of life  Meta-analysis
基金项目:上海市公共卫生重点学科建设计划资助项目(12GWZX0901);国家社会科学基金项目(项目类别:青年项目)(13CSH076)
作者单位
宫霄欢 复旦大学公共卫生学院临床流行病学研究中心公共卫生安全教育部重点实验室 
余金明 复旦大学公共卫生学院临床流行病学研究中心公共卫生安全教育部重点实验室 
王继伟 复旦大学公共卫生学院临床流行病学研究中心公共卫生安全教育部重点实验室 
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中文摘要:
      摘 要:[目的] 用Meta分析的方法综合定量评价社会心理干预影响乳腺癌患者生命质量的效果。[方法] 检索电子数据库收集相关随机对照试验(RCT),按纳入与排除标准筛选文献,以标准化均数差(SMD)为合并统计量,应用Stata11.0软件对干预后生命质量评分进行数据合并、异质性检验、敏感性分析。[结果] 纳入6项研究,658例研究对象,与对照组相比,干预组患者短期(<1个月)效果与对照组比较差异无统计学意义(SMD=0.202,95%CI:-0.093~0.496,P=0.180),经敏感性分析显示此结果稳定性较差;干预组患者中期(1~6个月)效果与对照组比较差异有统计学意义,生命质量提高(SMD=0.268,95%CI:0.101~0.436,P=0.002),且此结果稳定性较好。[结论] 乳腺癌患者接受社会心理干预后,中期生命质量得到改善,短期效果不明确。社会心理干预可以作为乳腺癌三级预防的实施内容。
英文摘要:
      Abstract:[Purpose] To evaluate the effect of psychosocial interventions on quality of life in patients with breast cancer by Meta-analysis.[Methods] Related randomized controlled trials (RCTs) were collected according to inclusion and exclusion criteria. Stata 11.0 was applied for combining the standardized mean difference(SMD),determining heterogeneity and sensitivity analysis. [Results] Six RCTs and 658 patients were included. The short-term(less than 1 month) quality of life of intervention group was not better than control group(SMD=0.202,95%CI:-0.093~0.496,P=0.180),sensitivity analysis showed that this result was less stable. The middle-term (1~6 months) quality of life of intervention group was better than control group(SMD=0.268,95%CI:0.101~0.436,P=0.002).[Conclusion] After receiving psychosocial interventions,the middle-term quality of life in patients with cancer breast is improved,while the short-term effect is unclear. Psychosocial interventions can be implemented as tertiary prevention content in breast cancer patients.
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