马雪曼,张培彤.CD133肿瘤干细胞标志物在肺癌中的应用进展[J].中国肿瘤,2014,23(3):224-227. |
CD133肿瘤干细胞标志物在肺癌中的应用进展 |
Progress in CD133 as Cancer Stem Cell Markers in Lung Cancer |
投稿时间:2013-05-20 |
DOI:10.11735/j.issn.1004-0242.2014.03.A011 |
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中文关键词: CD133 肺癌 肿瘤干细胞 肿瘤干细胞标志物 |
英文关键词:CD133 lung cancer cancer stem cells cancer stem cell markers |
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摘要点击次数: 1948 |
全文下载次数: 1278 |
中文摘要: |
摘 要:CD133作为肿瘤干细胞标志物已被广泛应用于临床,在肺癌干细胞的分选中亦具有重要作用。全文就肿瘤干细胞概念、CD133基因和结构、CD133与肿瘤干细胞的关系、CD133的临床应用以及CD133作为肿瘤干细胞标志物的局限性作一综述。 |
英文摘要: |
Abstract:As a marker of cancer stem cells,CD133 has been widely used in clinical,especially in lung cancer stem cells which plays an important role in cell selected. In this paper,the concept of tumor stem cell,CD133 gene and its structure,relationship of CD133 with cancer stem cells,usage of CD133 for clinic and the limitation of CD133 as cancer stem cell markers are reviewed. |
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