丁久香,张红燕.甲状腺结节钙化对甲状腺癌的诊断价值[J].中国肿瘤,2013,22(6):477-480.
甲状腺结节钙化对甲状腺癌的诊断价值
The Role of Thyroid Nodule with Calcification in the Diagnosis for Thyroid Carcinoma
投稿时间:2013-01-26  
DOI:10.11735/j.issn.1004-0242.2013.06.A201302067
中文关键词:  甲状腺结节  甲状腺肿瘤  超声检查  钙化
英文关键词:thyroid nodule  thyroid carcinoma  ultrasonagraphy  calcification
基金项目:
作者单位
丁久香 襄阳职业技术学院附属医院 
张红燕 襄阳市中心医院 
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中文摘要:
      摘 要:[目的] 探讨甲状腺结节合并钙化与甲状腺癌的关系。[方法] 回顾性分析 2007年1月至2012年11月197例甲状腺患者的彩色超声资料与病理诊断结果。[结果] 197例甲状腺结节中,钙化率为41.6%(82/197),其中甲状腺良性疾病中钙化率为21.4%(27/126),而在甲状腺癌中钙化率达77.5%(55/71)(χ2=58.684,P<0.001)。钙化诊断甲状腺癌的ROC曲线下面积为0.780(95%CI:0.710~0.850),其中微钙化ROC曲线下面积为0.748(95%CI:0.672~0.823),粗钙化ROC曲线下面积为0.625(95%CI:0.540~0.710)。[结论] 钙化尤其是微钙化对于甲状腺癌的诊断价值较高。
英文摘要:
      Abstract:[Purpose] To investigate the relationship between thyroid nodule with calcification and thyroid carcinoma. [Methods] The ultrasonagraphy and pathological data of 197 patient with thyroid carcinoma from January,2007 to November,2012 were retrospectively analyzed. [Results] Among 197 patients,the rate of calcification in thyroid nodule was 41.6%(82/197). The rate of calcification in thyroid carcinoma was 77.5%(55/71),and 21.4%(27/126) in benign thyroid nodule(χ2=58.684,P<0.001). The area of ROC curve of calcification for diagnosis of thyroid carcinoma was 0.780(95%CI:0.710~0.850),while the area of ROC curve of microcalcification was 0.748(95%CI:0.672~0.823),and macrocalcification was 0.625(95%CI:0.540~0.710).[Conclusions] Presence of calcification in thyroid nodule,especially microcalcification is valuable for the diagnosis of thyroid carcinoma.
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