| 于 雷.晚期肿瘤患者深静脉血栓形成的危险因素分析[J].中国肿瘤,2012,21(12):956-959. |
| 晚期肿瘤患者深静脉血栓形成的危险因素分析 |
| An Analysis on Risk Factors for Deep Venous Thrombosis in Patients with Advanced Cancer |
| 投稿时间：2012-08-27 |
| DOI： |
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| 中文关键词: 恶性肿瘤 深静脉血栓 危险因素 输血 感染 |
| 英文关键词:cancer deep venous thrombosis risk factors transfusion infection |
| 基金项目: |
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| 摘要点击次数: 1325 |
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| 中文摘要: |
| 摘 要：［目的］ 探讨晚期肿瘤患者发生深静脉血栓的危险因素。［方法］ 采用回顾性分析方法，对2005年1月至2010年12月期间发生深静脉血栓的78例晚期肿瘤患者的临床资料进行分析，同时随机选择同期不伴有血栓性疾病的78例恶性肿瘤患者为对照，分析晚期肿瘤患者深静脉血栓形成的危险因素。［结果］ 多因素分析显示，并发感染（OR=3.249，P=0.038）、输血(OR=1.460，P=0.041)及远处转移(OR=7.376，P＜0.001)是晚期肿瘤患者发生深静脉血栓的独立危险因素，病例组1年生存率明显低于对照组（41.0% vs 52.6%，χ2＝4.991，P=0.025）。［结论］ 远处转移、并发感染、输血治疗是晚期肿瘤患者发生深静脉血栓的危险因素，发生深静脉血栓者预后较差。 |
| 英文摘要: |
| Abstract:［Purpose］ To investigate the risk factors for deep venous thrombosis (DVT) in patients with advanced cancer. ［Methods］ The clinical data of 78 advanced cancer patients(observation group) with DVT from January 2005 to December 2010 were analyzed retrospectively. And 78 advanced cancer patients without DVT were selected as the control group. The risk factors for DVT in patients with advanced cancer were analyzed.［Results］ Multiple factor analysis showed that complicated with infection (OR=3.249，P=0.038)，blood transfusion (OR=1.460，P=0.041) and distant metastasis (OR=7.376，P＜0.001) were the independent risk factors to advanced cancer patients with DVT. The 1-year survival rate in observation group was lower than that in control group (41.0% vs 52.6%，P=0.025). ［Conclusion］ Distant metastasis，infection and blood transfusion are the risk factors for DVT in patients with advanced cancer，and the prognosis of patients with DVT is poor. |
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