| Abstract:［Purpose］To analyze the incidence and mortality of lymphoma in Hunan cancer registration areas in 2022, as well as their temporal trends from 2012 to 2022.［Methods］Data on the incidence and mortality of lymphoma in Hunan cancer registration areas from 2012 to 2022 were collected. Joinpoint regression analysis was performed to assess temporal trends, and the average annual percentage change (AAPC) with corresponding 95% confidence intervals (CIs) were estimated. Age-specific distribution patterns were also analyzed.［Results］In 2022, the overall incidence rate was 11.74 per 100,000 population (ASIRC: 7.64 per 100,000) and the mortality rate was 5.53 per 100,000 population (ASMRC: 3.06 per 100,000), with higher rates in males and urban areas than in females and rural areas. From 2012 to 2022, ASIRC (AAPC=4.52%) and ASMRC (AAPC=4.53%) both increased significantly, with a more pronounced increase in incidence among females (AAPC=5.91%) and in rural areas (AAPC=8.18%). Mortality also rose significantly in both genders and in rural areas. Age-specific incidence was low before age 25 (higher in the <1?year group than in the 1–24?year group), increased with age after 25 years, peaked at 75–79 years, and declined after 80 years. Age-specific mortality increased gradually after age 35 and peaked at 75–79 years. Urban incidence was significantly higher than rural incidence among people aged over 50 years, and urban mortality was significantly higher than rural mortality among those aged over 70 years.［Conclusion］From 2012 to 2022, lymphoma incidence and mortality in Hunan cancer registration areas showed an overall upward trend, with higher levels in males and urban areas, but a faster increase in incidence among females and in rural areas. Incidence and mortality increased with age and peaked at 75–79 years. |
