| Oral cancer has become a major public health issue in China. Its development is closely associated with long-term cumulative exposure to specific physicochemical carcinogens. Currently, due to insufficient public awareness of early prevention and the lack of standardized screening protocols, a large proportion of patients are already at advanced stages at initial diagnosis, resulting in poor overall prognosis. To promote the homogenization and standardization of early diagnosis and treatment of oral cancer in China and to reduce disease?specific mortality, the Hunan Cancer Prevention and Control Center (Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University), together with a multidisciplinary panel of national experts, developed this consensus based on the GRADE system and the modified Delphi method. This consensus explicitly defines high?risk populations via quantitative assessment of risk factors, establishes risk?stratified strategies for screening initiation age and frequency, standardizes the operational criteria for conventional oral examination and adjunctive technologies, and provides a closed?loop management pathway for the referral and follow?up of positive lesions. This consensus aims to provide scientific and practical guidance for oral cancer screening to medical institutions and public health departments at all levels |