|
| 2014-2022年贵州省主要消化系统恶性肿瘤发病特征及趋势分析 |
| Incidence Trends of Major Digestive system cancer in Guizhou Province from from 2014 to 2022 |
| 投稿时间：2026-03-02 修订日期：2026-05-06 |
| DOI： |
|
 |
| 中文关键词: 消化系统恶性肿瘤 发病率 变化趋势 贵州 |
| 英文关键词:Digestive system cancer Incidence Trends Guizhou |
| 基金项目:基金项目：贵州省卫生健康委培育在西南地区有影响力的重点优势学科；贵州省卫生健康委科学技术基金（gzwkj2025-525）；贵州省疾病预防控制中心新技术新方法（2024-E-15技） |
|
| 摘要点击次数: 14 |
| 全文下载次数: 0 |
| 中文摘要: |
| [目的] 分析2014-2022年贵州省主要消化系统恶性肿瘤发病流行状况及变化趋势。[方法] 使用贵州省肿瘤登记平台收集的2014-2022年主要消化系统恶性肿瘤发病资料，分年龄、性别、城乡计算发病粗率及中国人口标化率（简称中标率）。应用Joinpoint 5.0.2分析主要消化系统恶性肿瘤的发病粗率及标化发病率变化趋势，计算平均年度变化百分比（average annual percentage change, AAPC）及95%可信区间（confidence interval,CI）。[结果] 贵州省2014-2022年主要消化系统恶性肿瘤新发病例共97 809例，2014和2022年的发病粗率分别为66.74/10万、68.65/10万，中标发病率分别为54.11/10万和45.35/10万。2014-2022年贵州省主要消化系统恶性肿瘤各年度男性粗发病率及中标发病率均高于女性，除2022年外，各年度农村地区粗发病率及中标发病率均高于城市地区，其整体（AAPC=-2.12%，95%CI：-4.12%~-0.08%，P=0.042）、男性（AAPC=-1.59%，95%CI：-3.00%~-0.16%，P=0.029）、农村地区（AAPC=-4.94%，95%CI：-6.75%~-3.10%，P< 0.001）中标发病率呈下降趋势。其中胃癌2014和2022年的发病粗率分别为14.02/10万和9.97/10万，中标发病率分别为11.14/10万和6.52/10万，肝癌2014和2022年的发病粗率分别为24.37/10万和20.46/10万，中标发病率分别为19.89/10万和14.74/10万。2014-2022年胃癌和肝癌各年度男性粗发病率及中标发病率均高于女性，肝癌各年度农村地区粗发病率及中标发病率均高于城市地区，胃癌和肝癌的整体及不同性别、不同地区中标发病率均呈下降趋势（P<0.05）。胆囊癌2014和2022年的发病粗率分别为1.47/10万和3.36/10万，中标发病率分别为1.16/10万和2.28/10万，除2014年外，各年份的女性粗发病率和中标发病率均高于男性，其整体、女性及农村地区中标发病率呈上升趋势（P<0.05）。食管癌2014和2022年的发病粗率分别为4.61/10万和5.61/10万，中标发病率分别为3.71/10万和3.62/10万，各年度男性粗发病率及中标发病率均高于女性，农村地区高于城市地区。结直肠癌2014和2022年的发病粗率分别为19.55/10万和24.54/10万，中标发病率分别为15.99/10万和17.03/10万，胰腺癌2014和2022年的发病粗率分别为2.72/10万和4.70/10万，中标发病率分别为2.21/10万和3.15/10万。2014-2022年结直肠癌、胰腺癌各年度男性粗发病率及中标发病率均高于女性。食管癌、结直肠癌、胰腺癌的整体、不同性别、不同地区中标发病率的变化趋势无统计学意义（P>0.05）。[结论] 贵州省主要消化系统恶性肿瘤发病总体呈下降趋势，胃癌、肝癌的发病率逐年下降，胆囊癌的发病率逐年升高，应对女性、老年人、农村地区人群等胆囊癌重点群体开展针对性防控措施。 |
| 英文摘要: |
| [Purpose] To analyze the incidence characteristics and trends of major digestive system cancer in Guizhou Province from 2014 to 2022. [Methods] The incidence data of major digestive system cancer in Guizhou Province from 2014 to 2022 were collected from the Guizhou Cancer Registry Platform. The crude incidence rate (CIR) and age-standardized incidence rate by Chinese standard population (ASIRC) of major digestive system cancer were calculated by age, gender and urban -rural areas. Using the Joinpoint 5.0.2 software to calculate the average annual percentage change (AAPC) and 95% confidence interval (CI) to analyze the trends of the CIR rate and ASIRC. [Results] From 2014 to 2022, there were 97 809 new cases of major digestive system cancer in Guizhou Province, the CIR in 2014 and 2022 were 66.74/105 and 68.65/105, while ASIRC were 54.11/105 and 45.35/105, respectively. The annual CIR and ASIRC of major digestive system cancer were higher in male than those in female. Except for 2022, the CIR and ASIRC in rural area were higher than those in urban area in all years. The ASIRC showed a declining trend across the overall population (AAPC=-2.12%, 95%CI:-4.12%~-0.08%, P=0.042), among male (AAPC=-1.59%, 95%CI: -3.00%~-0.16%, P=0.029), and in rural area (AAPC=-4.94%, 95% CI:-6.75%~-3.10%, P <0.001).The CIR of gastric cancer in 2014 and 2022 were 14.02/105 and 9.97/105, respectively, while the ASIRC were 11.14/105 and 6.52/105, respectively. For liver cancer, the CIR in 2014 and 2022 were 24.37/105 and 20.46/105, respectively, with the ASIRC were 19.89/105 and 14.74/105. From 2014 to 2022, both the annual CIR and ASIRC of gastric cancer and liver cancer in male were higher than those in female. For liver cancer, the annual CIR and ASIRC in rural area were higher than that in urban area. The overall ASIRC, as well as those by gender and region, all showed a declining trends (P<0.05). For gallbladder cancer, the CIR in 2014 and 2022 were 1.47/105 and 3.36/105, respectively, while the ASIRC were 1.16/105 and 2.28/105, respectively. Except for 2014, the CIR and ASIRC in female were higher than those in male in all years. From 2014 to 2022, The overall ASIRC, as well as those among female and rural area, all showed a declining trends (P<0.05). The CIR of esophageal cancer in 2014 and 2022 were 4.6/105 and 5.61/105, respectively, while the ASIRC were 3.71/105 and 3.62/105. In all years, both the CIR and ASIRC were higher in male than in female, and higher in rural area than in urban area. The CIR of colorectal cancer in 2014 and 2022 were 19.55/105 and 24.54/105, respectively, with ASIRC of 15.99/105 and 17.03/105. The CIR of pancreatic cancer in 2014 and 2022 were 2.72/105 and 4.70/105, respectively, with ASIRC of 2.21/105 and 3.15/105. From 2014 to 2022, both the CIR and ASIRC of colorectal cancer and pancreatic cancer were higher in male than in female. No statistically significant trends were observed in the overall, gender-specific, or region-specific ASIRC of esophageal cancer, colorectal cancer, and pancreatic cancer (P>0.05). [Conclusion] The incidence of major digestive system cancer in Guizhou has shown a downward trend, with the incidence of gastric cancer and liver cancer declining, while that of gallbladder cancer has been increasing annually. It suggested that targeted prevention and control measures of gallbladder cancer should be implemented for key groups, particularly women, the elderly, and individuals living in rural area. |
|
在线阅读
查看/发表评论 下载PDF阅读器 |
|
|
|