| [Purpose] To analyze kidney cancer incidence and mortality in Zhejiang cancer registration areas in 2021 and the trends from 2000 to 2021. [Methods] The data of kidney cancer reported by the Zhejiang provincial cancer registries from 2000 to 2021 were collected. The crude incidence and mortality rates were calculated, along with age-standardized rates using the Chinese standard population (ASIRC and ASMRC) and the world standard population (ASIRW and ASMRW), as well as the cumulative rate (0~74 years) and the truncated rate (35~64 years), to characterize the current situation. The average annual percentage change (AAPC) was derived using the Join point regression model to the epidemiological analyze trend. [Results] In 2021, the ASIRC in Zhejiang Province was 5.51/105, of which 7.35/105 for males, 3.73/105 for females, 5.99/105 in urban areas and 4.76/105 in rural areas. The cumulative incidence rate(0~74 years) was 0.62%, and the truncated incidence rate(35~64 years) was 9.75/105. The ASMRC was 1.01/105, of which 1.38/105 for men, 0.66/105 for females, 1.01/105 in urban areas and 1.02/105 in rural areas. The cumulative mortality rate(0~74 years) was 0.09% and the truncated mortality rate (35~64 years) was 1.02/105. Incidence and mortality rates were higher for males than for females, and higher in urban than in rural areas. Incidence rates continued to increase rapidly with age after 25 years, with males and urban areas increasing faster than females and rural areas, and the growth rate began to slow down after 65 years, reaching a peak at 70-79 years. The mortality rate continued to increase rapidly with age after 50 years, with males and urban areas increasing at a faster rate than females and rural areas, except for rural females, where the rate of increase did not slow down significantly, peaking in the age group of 85 years or older. The incidence rate of kidney cancer showed an increasing trend year by year from 2000 to 2021 (AAPC=2.79 %, 95%CI: 1.76% ~ 3.87%, P<0.05), with the fastest increase in the rural males (AAPC=13.63 %, 95%CI: 9.52% ~ 16.78%, P<0.05). The mortality rate of kidney cancer showed an increasing trend year by year from 2000 to 2021 (AAPC=2.44%, 95%CI: 1.18% ~ 3.73%, P<0.05), with the fastest increase in rural females (AAPC=52.79%, 95%CI: 26.58% ~ 71.42%, P<0.05). [Conclusion] The incidence of kidney cancer in Zhejiang cancer registration areas was relatively high, with both incidence and mortality rates showing an upward trend that warrants attention. Urban males constitute the primary target group for prevention and control efforts. |
