2021年浙江省子宫颈癌发病死亡现状及2000-2021年变化趋势分析
Analysis of incidence and mortality of cervical cancer in Zhejiang Province in 2021 and trends from 2000 to 2021
投稿时间:2025-06-24  修订日期:2025-08-25
DOI:
中文关键词:  子宫颈癌  发病率  死亡率  流行趋势  浙江省
英文关键词:cervical cancer  incidence  mortality  trend  Zhejiang Province
基金项目:
作者单位邮编
王玲娜 温岭市疾病预防控制中心 317500
吴丹红 温岭市疾病预防控制中心 317500
方主未 温岭市疾病预防控制中心 317500
李辉章* 浙江省肿瘤医院 310022
杜灵彬 浙江省肿瘤医院 310022
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中文摘要:
      [目的] 分析2021年浙江省子宫颈癌发病死亡现状及2000-2021年流行变化趋势。[方法] 收集浙江省22个肿瘤登记处上报的子宫颈癌发病与死亡资料,计算发病和死亡粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、0-74岁累积率以及35-64岁截缩率等指标。根据2000年全国普查标准人口构成计算中标率,根据Segi"s世界标准人口构成计算世标率。采用Joinpoint模型计算分析2000-2021年浙江省子宫颈癌发病和死亡趋势,计算年度变化百分比(annual percentage change,APC)、平均年度变化百分比(average annual percentage change,AAPC)及其95%可信区间(95%CI)。[结果] 2021年浙江省女性子宫颈癌粗发病率为17.71/10万,中标发病率为11.17/10万,世标发病率为10.27/10万;粗死亡率为4.27/10万,中标死亡率为2.11/10万,世标死亡率为2.33/10万。年龄别发病与死亡率均随着年龄增加而上升,发病率在50-54岁(31.19/10万)及70-74岁组(35.55/10万)出现双高峰,死亡率在80-84岁组出现最高峰(24.81/10万)。2000-2021年中标发病率总AAPC为4.02%(95%CI:3.07~4.96),农村中标发病率(AAPC=8.40%,95%CI:6.75~10.04)的上升幅度高于城市(AAPC=2.71%,95%CI:1.60~3.9)。中标死亡率的总AAPC为4.51%(95%CI:2.04~7.71),其中2000-2015年呈增长趋势(APC=7.24%,P<0.05),2015-2021年呈略微下降趋势(APC=-2.02%,P>0.05,无统计学意义)。[结论] 2002-2021年浙江省子宫颈癌的发病与死亡总体呈上升趋势,其中农村发病率的上升幅度高于城市,防治工作仍需重视。
英文摘要:
      [Purpose] To analyze the incidence and mortality of cervical cancer in cancer registration areas of Zhejiang Province in 2021 and the trend from 2000 to 2021. [Methods] Incidence and mortality data of cervical cancer by twenty-two cancer registration areas in Zhejiang in 2021 were collected. Crude incidence and mortality rates, age-standardized incidence and mortality rates by Chinese standard population (ASIRC/ ASMRC), and world standard population(ASIRW/ASMRW), and cumulative rate (0~74years old) were calculated. The Chi-nese standard population (2000 national census) and Segi"sworld standard popu-lation were used for standardization, The Joinpoint model was used to analyze the trends of incidence and mortality from 2000 to 2021 and calculate the an-nual percentage change (APC) 、average annual percentage change (AAPC) andthe 95%CI. [Results]In 2021,the crude incidence of cervical cancer among wo-men in Zhejiang Province was 17.71/105, the ASIRC was 11.17/105, and the ASIRW was 10.27/105; the crude mortality rate was 4.27/105, the ASMRC was2.11/105, and the ASMRW was 2.33/105. Both incidence and mortality increas-ed with age,with two Peaks in the incidence rate at age 50-54(31.19/105) and age 70-74 (35.55 / 105) , and the mortality rate Peaked at age 80-84(24.81/105). The AAPC of the ASIRC of cervical cancer among women in Zhejiang Provi-nce from 2000 to 2021 was 4.02%(95%CI:3.07~4.96). Moreover, the increa se in the rural areas incidence rate(AAPC=8.40%,95%CI:6.75~10.04) was significa-ntly higher than that in urban areas (AAPC=2.71%,95%CI:1.60~3.9). The over-all AAPC for ASMRC was 4.51% (95% CI: 2.04~ 7.71). From 2000 to 2015,there was a growing trend (APC=7.24%, P<0.05),and from 2015 to 2021, therewas a slightly declining trend(APC=-2.02%, P>0.05, no statistical significance). [Conclusion]From 2002 to 2021, both the incidence and mortality rates of cervi-cal cancer in Zhejiang Province showed an upward trend. The incidence rate inrural areas is higher than that in urban areas, and prevention and treatment work still needs attention.
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