| Abstract: [Objective] To analyze the screening results of upper gastrointestinal cancer in the northeastern Sichuan region (Langzhong City, Cangxi County, Nanbu County, and Xichong County) from 2015 to 2023, and to provide a basis for optimizing the population screening strategy. [Method] Based on the questionnaire survey and endoscopic screening data of permanent residents aged 40 to 69, the detection rates of various levels of lesions in the esophagus, cardia and stomach, the detection rate of positive cases (precancerous lesions and above), the detection rate of early cases and the early diagnosis rate were analyzed. The χ2 test was used to analyze the differences in positive detection rates among different genders, ages and time periods. All lesions were pathologically confirmed. [Result] From 2015 to 2023, a total of 74,403 people were screened in 4 counties and cities. The detection rate of lesions at all levels of the upper digestive tract was 5.69% (4237/74403), among which the detection rates of lesions at all levels of the esophagus, cardia and stomach were 3.48% (2588/74403), 0.57% (427/74403) and 1.75% (1302/74403), respectively. The detection rate of positive cases in the upper digestive tract was 1.46% (1087/74403), the detection rate of early cases was 1.26% (939/74403), and the early diagnosis rate reached 86.38% (939/1087). The detection rates of lesions at all levels in males were significantly higher than those in females (P<0.05). The detection rate increased with age (P<0.05). The detection rates of lesions at all levels of the upper digestive tract and esophagus showed a characteristic of first increasing (from 2015 to 2020) and then decreasing (from 2021 to 2023). From 2015 to 2023, the detection rates of various levels of lesions in the cardia and stomach showed a downward trend (P<0.05). [Conclusion] The screening for upper gastrointestinal cancer in the northeastern Sichuan region has achieved remarkable results (early diagnosis rate >86%). In the future, it is necessary to focus on enhancing the screening participation of men over 55 years old, while paying attention to the incidence trends of cardia cancer and gastric cancer, in order to further increase the early detection rate of cancer and improve prognosis. |
