河北省2012年-2020年肺癌流行特征及疾病负担
Prevalence Characteristics and Disease Burden of Lung Cancer in Hebei Province from 2012 to 2020
投稿时间:2025-01-06  修订日期:2025-04-09
DOI:
中文关键词:  肺癌,发病率,死亡率,疾病负担
英文关键词:lung cancer  incidence  mortality  burden of disease
基金项目:河北省重点研发计划
作者单位邮编
付艳芳 河北医科大学第四医院 050011
李道娟 河北医科大学第四医院 050011
刘言玉 河北医科大学第四医院 050011
闫志强 河北医科大学第四医院 050011
贺宇彤* 河北医科大学第四医院 050000
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中文摘要:
      【【摘要】:[目的] :本研究通过收集2012-2020年河北省肺癌发病死亡数据,描述分析河北省肺癌流行情况,探究流行特征及疾病负担。[方法]:收集2012-2020年河北省肿瘤登记处肺癌数据,并合并汇总分析,计算各年份发病(死亡)例数、发病(死亡)率、中国人口年龄标化率(以下简称“中标率”)、世界人口年龄标化率(以下简称“世标率”)和年龄别发病(死亡)率等指标。采用2000年中国标准人口构成和Segi’s世界标准人口构成对数据进行标化,计算城乡男女年龄别发病(死亡)率、标化发病(死亡)率,使用Joinpoint模型计算肺癌世标发病率及死亡率年度变化百分比(APC)和平均年度变化百分比(AAPC),计算伤残调整寿命年(DALY)、YLL和YLD以及相关率。[结果] :2012-2020年间河北省肺癌世标发病率为33.13/10万,男女发病率分别为44.56 /10万和22.54 /10万,2012-2020年发病死亡率呈下降趋势。城乡发病率分别29.05 /10万和33.52/10万,年龄别发病率在80~84岁年龄段达到峰值。城市发病率低于农村,城乡发病呈下降趋势。2012-2020年世标死亡率为25.80/10万,男女死亡率分别为36.56/10万和15.96 /10万。城乡死亡率分别25.14/10万和26.12 /10万,年龄别死亡率在80~84岁年龄段达到峰值,2015年后农村发病死亡率反超城市地区,中老年人发病死亡负担逐渐加重。2012-2020年河北省因肺癌死亡人数为57584人,占所有癌症死亡病例数的23.31%,其中男性38679人(67.17%),女性18905人(32.83%)。2012-2020年河北省肺癌DALY为484194人年,男性占66.77%,女性占33.23%,肺癌DALY率为3.31‰,相当于每一千名居民损失了3.31个健康寿命年,其中城市地区占35.57%,农村地区占64.43% [结论] :2012-2020年河北省肺癌发病死亡率呈下降趋势,男性发病死亡率高于女性,2015年后农村发病死亡率反超城市地区中老年人发病死亡负担逐渐加重。我们应加强肺癌相关危险因素的宣传教育,提高癌症防治素养,降低疾病负担。
英文摘要:
      【Abstract】:[Objective]: This study describes and analyzes the prevalence of lung cancer in Hebei Province by collecting data on the incidence and death of lung cancer from 2012 to 2020, exploring the prevalence characteristics and the burden of disease. [Methods] : Lung cancer data were collected from the Hebei Provincial Tumor Registry from 2012 to 2020, combined and analyzed, and the number of cases of incidence (death), incidence (death) rate, age-standardized rate of China's population (hereinafter referred to as “CSR”), age-standardized rate of the world's population (hereinafter referred to as “WSR”), and the incidence (death) rate of the world's population (hereinafter referred to as “WSR”) were calculated for each year. (hereinafter referred to as the “world standardized rate”) and age-specific morbidity (mortality) rates. The data were standardized using the 2000 Chinese Standard Population Composition and Segi's World Standard Population Composition to calculate the age-specific incidence (mortality) rates and standardized incidence (mortality) rates for urban and rural men and women, and the Joinpoint model was used to calculate the annual percentage change (APC) and average annual percentage change (AAPC) in the incidence and mortality rates for the world-standardized rates of lung cancer, and the disability-adjusted annual percentage change and calculate disability-adjusted life-years (DALY), YLL and YLD, and correlation rates. [Results] : During 2012-2020, the incidence rate of lung cancer in Hebei Province is 33.13/100,000, and the incidence rates of men and women are 44.56/100,000 and 22.54/100,000 respectively, and the incidence and mortality rates are on a decreasing trend from 2012 to 2020; the incidence rates of urban and rural areas are 29.05/100,000 and 33.52/100,000 respectively, and the incidence rates of different age groups reach the peak in the age group of 80-84 years old. The morbidity and mortality rates in urban areas are lower than those in rural areas, and there is a decreasing trend in urban and rural areas. 2012-2020, the mortality rate of the World Health Organization (WHO) is 25.80/100,000, and the mortality rates of men and women are 36.56/100,000 and 15.96/100,000, respectively; the mortality rates of urban and rural areas are 25.14/100,000 and 26.12/100,000, respectively; the mortality rates of age-specific diseases peak in the age group of 80-84 years old, and the mortality rates of rural areas will exceed those of urban areas after 2015. After 2015, the morbidity and mortality rate in rural areas exceeded that in urban areas. The burden of morbidity and mortality among middle-aged and elderly people is gradually increasing. The number of deaths due to lung cancer in Hebei Province from 2012 to 2020 is 57,584, accounting for 23.31% of all cancer deaths, of which 38,679 (67.17%) are male and 18,905 (32.83%) are female. The DALY of lung cancer in Hebei Province from 2012 to 2020 is 484,194 person-years, with males accounting for 66.77%, female accounted for 33.23%, the rate of lung cancer DALY is 3.31‰, corresponds to a loss of 3.31 healthy life years per 1,000 inhabitants, of which 35.57% in urban areas and 64.43% in rural areas. [Conclusion]: Lung cancer incidence and mortality rate in Hebei Province from 2012 to 2020 showed a decreasing trend, with male incidence and mortality rate higher than female, and rural incidence and mortality rate exceeded urban areas after 2015. The burden of morbidity and mortality among middle-aged and elderly people is gradually increasing. We should strengthen the publicity and education of lung cancer-related risk factors, improve cancer prevention and treatment literacy, and reduce the burden of disease.
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